Anne Cress, PhD

Deputy Dean, Research Affairs
Professor, Cellular and Molecular Medicine
Professor, Radiation Oncology
Professor, Molecular and Cellular Biology
Research Interests: 

My research is to understand the molecular mechanisms of cell adhesion and human tumor metastasis. We discovered cell adhesion adaptive responses of tumors dependent upon adhesion receptors called integrins. The adaptive responses are essential for normal tissue development but are used for nepharious purposes in cancer. We use tools of biochemistry, cell biology and genetics.

Molecular Medicine Grad Program: 
Yes

Bibliography

2016

Sroka, I. C., H. Chopra, L. Das, J. M. C. Gard, R. B. Nagle, and A. E. Cress, "Schwann Cells Increase Prostate and Pancreatic Tumor Cell Invasion Using Laminin Binding A6 Integrin.", J Cell Biochem, vol. 117, issue 2, pp. 491-9, 2016 Feb. PMCID: PMC4809241  PMID: 26239765
WL, H., and P. E, Laminin-binding integrin gene copy number alterations in distinct epithelial-type cancers. Am J Transl Res 2016;8(2):940-954., , 2016.
Wang, M., R. B. Nagle, B. S. Knudsen, G. C. Rogers, and A. E. Cress, "A basal cell defect promotes budding of prostatic intraepithelial neoplasia.", J Cell Sci, 2016 Sep 8. PMID: 27609833

2015

Chen, W., Y. Epshtein, X. Ni, R. O. Dull, A. E. Cress, J. G. N. Garcia, and J. R. Jacobson, "Role of Integrin β4 in Lung Endothelial Cell Inflammatory Responses to Mechanical Stress.", Sci Rep, vol. 5, pp. 16529, 2015. PMCID: PMC4647208  PMID: 26572585
Geffre, C. P., E. Pond, G. D. Pond, I. C. Sroka, J. M. Gard, B. A. Skovan, W. E. Meek, T. H. Landowski, R. B. Nagle, and A. E. Cress, "Combined micro CT and histopathology for evaluation of skeletal metastasis in live animals.", Am J Transl Res, vol. 7, issue 2, pp. 348-55, 2015. PMCID: PMC4399097  PMID: 25901201

2014

Landowski, T. H., J. Gard, E. Pond, G. D. Pond, R. B. Nagle, C. P. Geffre, and A. E. Cress, "Targeting integrin α6 stimulates curative-type bone metastasis lesions in a xenograft model.", Mol Cancer Ther, vol. 13, issue 6, pp. 1558-66, 2014 Jun. PMCID: PMC4069206  PMID: 24739392