My research is to understand the molecular mechanisms of cell adhesion and human tumor metastasis. We discovered cell adhesion adaptive responses of tumors dependent upon adhesion receptors called integrins. The adaptive responses are essential for normal tissue development but are used for nepharious purposes in cancer. We use tools of biochemistry, cell biology and genetics.
Anne Cress, PhD
Deputy Dean, Research Affairs
Professor, Cellular and Molecular Medicine
Professor, Radiation Oncology
Professor, Molecular and Cellular Biology
Molecular Medicine Grad Program:
WL, H., and P. E, Laminin-binding integrin gene copy number alterations in distinct epithelial-type cancers. Am J Transl Res 2016;8(2):940-954., , 2016.
Wang, M., R. B. Nagle, B. S. Knudsen, G. C. Rogers, and A. E. Cress, "A basal cell defect promotes budding of prostatic intraepithelial neoplasia.", J Cell Sci, 2016 Sep 8. PMID: 27609833
Geffre, C. P., E. Pond, G. D. Pond, I. C. Sroka, J. M. Gard, B. A. Skovan, W. E. Meek, T. H. Landowski, R. B. Nagle, and A. E. Cress, "Combined micro CT and histopathology for evaluation of skeletal metastasis in live animals.", Am J Transl Res, vol. 7, issue 2, pp. 348-55, 2015. PMCID: PMC4399097 PMID: 25901201