Many cancer cells - as cause or consequence of their disease state - undergo hypermutation and genomic instability. My laboratory is interested in how and why these events occur, and how they enable cancer development and progression. We focus on the repetitive ribosomal RNA genes to understand how epigenetic inheritance, gene regulation, and genome stability are linked together such that defects in one result in defects in the others.
Keith Maggert, PhD
Associate Professor, Cellular and Molecular Medicine
Molecular Medicine Grad Program: