Ritu Pandey, MSc, PhD

Assistant Research Professor, Cellular and Molecular Medicine
Associate Director, Translational Clinical Bioinformatics
Coordinator, Biomedical Informatics
Research Interests: 

Data driven research. Our interest is to investigate underlying molecular events in tumor cohorts by integrated computational analysis of clinical and molecular data from multi-omics projects. Translate the datasets into insights that advance understanding of biomarkers/therapeutic targets and response to treatment. Current focus is to evaluate stratified patient populations for transcriptome, proteome and immune signatures in colorectal tumor with specific gene mutations.

Molecular Medicine Grad Program: 
No

Bibliography

2021

Cheng, J. N., J. B. Frye, S. A. Whitman, A. G. Kunihiro, R. Pandey, and J. L. Funk, "A Role for TGFβ Signaling in Preclinical Osteolytic Estrogen Receptor-Positive Breast Cancer Bone Metastases Progression.", Int J Mol Sci, vol. 22, issue 9, 2021 Apr 24. PMCID: PMC8123146  PMID: 33923316
Singh, N., V. R. Ramnarine, J. H. Song, R. Pandey, S. K. R. Padi, M. Nouri, V. Olive, M. Kobelev, K. Okumura, D. McCarthy, et al., "The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer.", Nat Commun, vol. 12, issue 1, pp. 7349, 2021 Dec 21. PMID: 34934057
Pandey, R., N. Johnson, L. Cooke, B. Johnson, Y. Chen, M. Pandey, J. Chandler, and D. Mahadevan, "Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients.", Cancers (Basel), vol. 13, issue 4, 2021 Feb 03. PMID: 33546249
Rico, K., S. Duan, R. L. Pandey, Y. Chen, J. T. Chakrabarti, J. Starr, Y. Zavros, T. Else, B. W. Katona, D. C. Metz, et al., "Genome analysis identifies differences in the transcriptional targets of duodenal versus pancreatic neuroendocrine tumours.", BMJ Open Gastroenterol, vol. 8, issue 1, 2021 Nov. PMCID: PMC8576490  PMID: 34750164
Wusterbarth, E., Y. Chen, H. Jecius, E. Krall, R. B. Runyan, R. Pandey, and V. Nfonsam, "Cartilage Oligomeric Matrix Protein, COMP may be a Better Prognostic Marker Than CEACAM5 and Correlates With Colon Cancer Molecular Subtypes, Tumor Aggressiveness and Overall Survival.", J Surg Res, vol. 270, pp. 169-177, 2021 Oct 20. PMID: 34687957
Pandey, R., M. Zhou, Y. Chen, D. Darmoul, C. C. Kisiel, V. N. Nfonsam, and N. A. Ignatenko, "Molecular Pathways Associated with Kallikrein 6 Overexpression in Colorectal Cancer.", Genes (Basel), vol. 12, issue 5, 2021 05 16. PMCID: PMC8157155  PMID: 34065672

2020

Larson, K., R. Kannaiyan, R. Pandey, Y. Chen, H. M. Babiker, and D. Mahadevan, "A Comparative Analysis of Tumors and Plasma Circulating Tumor DNA in 145 Advanced Cancer Patients Annotated by 3 Core Cellular Processes.", Cancers (Basel), vol. 12, issue 3, 2020 03 16. PMCID: PMC7140098  PMID: 32188081
Singh, N., S. K. R. Padi, J. J. Bearss, R. Pandey, K. Okumura, H. Beltran, J. H. Song, A. S. Kraft, and V. Olive, "PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell gene transcription and modulate tumor growth.", Mol Oncol, 2020 03 07. PMID: 32146726
Iesa, M. Am, M. Em Osman, M. A. Hassan, A. Ia Dirar, N. Abuzeid, J. J. Mancuso, R. Pandey, A. A. Mohammed, M. J. Borad, H. M. Babiker, et al., "SARS-COV2 and common immunodominant regions may explain low COVID-19 incidence in the malaria-endemic belt.", New Microbes New Infect, pp. 100817, 2020 Nov 19. PMCID: PMC7674012  PMID: 33230417

2019

Pandey, R., H-H. Woo, F. Varghese, M. Zhou, and S. K. Chambers, "Circulating miRNA Profiling of Women at High Risk for Ovarian Cancer.", Transl Oncol, vol. 12, issue 5, pp. 714-725, 2019 05 01. PMCID: PMC6411608  PMID: 30856556
Song, J. H., H-J. Kang, L. A. Luevano, V. Gokhale, K. Wu, R. Pandey, H-H. Sherry Chow, L. H. Hurley, and A. S. Kraft, "Small-Molecule-Targeting Hairpin Loop of hTERT Promoter G-Quadruplex Induces Cancer Cell Death.", Cell Chem Biol, 2019 05 13. PMID: 31155510
Chen, H., E. Sells, R. Pandey, E. R. Abril, C-H. Hsu, R. S. Krouse, R. B. Nagle, G. Pampalakis, G. Sotiropoulou, and N. A. Ignatenko, "Kallikrein 6 protease advances colon tumorigenesis induction of the high mobility group A2 protein.", Oncotarget, vol. 10, issue 58, pp. 6062-6078, 2019 10 22. PMCID: PMC6817440  PMID: 31692974
Pandey, R., M. Zhou, S. Islam, B. Chen, N. K. Barker, P. Langlais, A. Srivastava, M. Luo, L. S. Cooke, E. Weterings, et al., "Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) in Pancreatic Ductal Adenocarcinoma (PDA): An integrative analysis of a novel therapeutic target.", Sci Rep, vol. 9, issue 1, pp. 18347, 2019 12 04. PMID: 31797958