Nathan Ellis, PhD
Aberrant DNA Replication and Genomic Instability
A Thriving Environment for Biomedical Discovery
Gus Mouneimne, PhD
Understanding How Cytoskeletal Architecture Regulates Cancer Metastasis
Jean Wilson, PhD
Cell biology of barrier function in inflammatory bowel diseases
Brett Colson, PhD
Deciphering the Structural Basis for Muscle Contraction at the Molecular Level
Greg Rogers, PhD
Investigating Mechanisms of Genomic Integrity
Tom Doetschman, PhD
Synergistic activities of TGFbeta deficiency and the gut microbiome in colon cancer.
Samantha Harris, PhD
Understanding myosin binding protein-C in health and disease
Casey Romanoski, PhD
Systems Genetics Approaches to Identify Mechanisms of Complex Diseases
Keith Maggert, PhD
Understanding the Origins of Genome Instability
In a recent study led by UA Assistant Professor Casey Romanoski, PhD, the research team used genome-wide epigenetics to identify major drivers of human artery endothelial cell responses to inflammatory environments. They utilized endothelial genome sequences called enhancers to pinpoint DNA variation in humans that may underpin differential susceptibility to coronary artery disease. Their findings, published June 6th in eLIFE (https://elifesciences.org/articles/22536), improve our understanding of vascular biology and moves us one step closer to understanding the molecular mechanisms of disease.
Congratulations to Dr. Keith Maggert who has received the prestigious NIH Director’s Transformative Research Award, a five-year $1.7 million grant from the National Institutes of Health to fund his project “Induced transgenerational inheritance without epigenetics”.
Congratulations to Kelvin Pond and John Ryniawec, our UA ARCS Foundation Scholars for 2017-18!