• Gus Mouneimne, PhD

    Understanding How Cytoskeletal Architecture Regulates Cancer Metastasis

  • Nathan Ellis, PhD

    Aberrant DNA Replication and Genomic Instability

  • Curtis Thorne, PhD

    Discovering Signals Controlling Cell Fate of Regenerative Tissues

  • DISCOVERY

    A Thriving Environment for Biomedical Discovery

  • LEADERS

    Training Our Next Leaders in Biomedical Research

  • Jared Churko, PhD

    Informatics to Understand Cardiovascular Development and Disease Mechanisms

  • Noel Warfel, PhD

    Modeling the Effects of Hypoxia on Cancer Cells and Tumor Angiogenesis

  • Keith Maggert, PhD

    Understanding the Origins of Genome Instability

  • Jean Wilson, PhD

    Cell biology of barrier function in inflammatory bowel diseases

  • Brett Colson, PhD

    Deciphering the Structural Basis for Muscle Contraction at the Molecular Level

  • RESEARCH

    An Established Leader in Cutting-edge Research

  • Samantha Harris, PhD

    Understanding Myosin Binding Protein-C in Health and Disease

  • Casey Romanoski, PhD

    Systems Genetics Approaches to Identify Mechanisms of Complex Diseases

  • Tom Doetschman, PhD

    Synergistic Activities of TGFbeta Deficiency and the Gut Microbiome in Colon Cancer

  • Greg Rogers, PhD

    Investigating Mechanisms of Genomic Integrity

Home

Message from the Chair

The mission of the Department of Cellular and Molecular Medicine (CMM) is to provide pre- and post-doctoral, medical and graduate education in an interdisplinary environment through research activities, to advance knowledge of biological structure as related to function and disease from the molecular level to the whole organism.

Announcements

Dr. Diana Darnell promoted to full Professor (July 2, 2018)

Congratulations to CMM's own Diana Darnell, PhD for her promotion to full Professor, Educator Scholar Track! 

Farah Bughio receives Donald G. Sheer Travel Award (June 26, 2018)

CMM would like to extend a warm congratulations to Farah Bughio (Maggert lab), recipient of a 2018 Donald G. Sheer Memorial Fund travel grant!  This fund provides stipends to graduate students to allow them to travel to scientific conferences and meetings in the health sciences to present their research.  Great job, Farah!

Dr. Curtis Thorne publishes in Developmental Cell (March 19, 2018)

Curtis Thorne, PhD, and colleagues published a new study in Developmental Cell describing a simple, scalable method to culture 2D enteroid monolayers that, surprisingly, recapitulates many of the features of in vivo intestinal tissue and can be used for high-throughput microscopy-based experiments. Using this system, they systematically perturb WNT and BMP signals to reveal a core morphogenic circuit that controls proliferation, tissue organization, and cell fate or the intestine.

Welcome to our new students! (March 16, 2018)

CMM is delighted to welcome the following new PhD students who are entering the Graduate Program in Molecular Medicine: Alice Solomon, (Romanoski Lab), Austin Conklin (Romanoski Lab) and Rhye-Samuel Kanassatega (Colson Lab).   We also extend a friendly welcome to the following Cancer Biology PhD students who will be working in labs with CMM faculty: Carly Cabel (Thorne Lab), Corbin Jensen (Warfel Lab) and Shekha Tahsin (Miranti Lab). 

Wilson lab part of multi-PI grant from NIAID to study cytomegalovirus control of host membrane trafficking (March 8, 2018)

Dr. Jean Wilson of Cellular & Molecular Medicine and Dr. Felicia Goodrum of Immunobiology have secured a 5 year grant from the National Institute of Allergy and Infectious Disease.  This $1.9M grant is entitled “Cytomegalovirus Control of Host Membrane Trafficking.” Cytomegalovirus is a major cause of birth defects and increases risk for vascular disease and other age-related pathologies. These funds will be used to study how the virus co-opts host cell membrane trafficking to promote its survival and replication. 

Rogers lab publication appears in the Journal of Cell Biology (March 6, 2018)

Tiffany McLamarrah, PhD, and colleagues publish new study on the regulation of centriole duplication.  Centriole duplication is tightly regulated throughout the cell cycle to ensure one duplication event per centriole. McLamarrah et al. show that a stepwise pattern of Ana2 phosphorylation by Plk4 facilitates proper centriole duplication providing molecular insight into the assembly process of this organelle.

Spotlight

An inspiration from THE DESERT – two team-building murals by CMM Faculty and Family. ​We had a blast at Creative Juice Bar on Tuesday evening (3/6/2018)!