Congratulations to CMM's own Diana Darnell, PhD for her promotion to full Professor, Educator Scholar Track!
CMM would like to extend a warm congratulations to Farah Bughio (Maggert lab), recipient of a 2018 Donald G. Sheer Memorial Fund travel grant! This fund provides stipends to graduate students to allow them to travel to scientific conferences and meetings in the health sciences to present their research. Great job, Farah!
Curtis Thorne, PhD, and colleagues published a new study in Developmental Cell describing a simple, scalable method to culture 2D enteroid monolayers that, surprisingly, recapitulates many of the features of in vivo intestinal tissue and can be used for high-throughput microscopy-based experiments. Using this system, they systematically perturb WNT and BMP signals to reveal a core morphogenic circuit that controls proliferation, tissue organization, and cell fate or the intestine.
CMM is delighted to welcome the following new PhD students who are entering the Graduate Program in Molecular Medicine: Alice Solomon, (Romanoski Lab), Austin Conklin (Romanoski Lab) and Rhye-Samuel Kanassatega (Colson Lab). We also extend a friendly welcome to the following Cancer Biology PhD students who will be working in labs with CMM faculty: Carly Cabel (Thorne Lab), Corbin Jensen (Warfel Lab) and Shekha Tahsin (Miranti Lab).
Dr. Jean Wilson of Cellular & Molecular Medicine and Dr. Felicia Goodrum of Immunobiology have secured a 5 year grant from the National Institute of Allergy and Infectious Disease. This $1.9M grant is entitled “Cytomegalovirus Control of Host Membrane Trafficking.” Cytomegalovirus is a major cause of birth defects and increases risk for vascular disease and other age-related pathologies. These funds will be used to study how the virus co-opts host cell membrane trafficking to promote its survival and replication.
Tiffany McLamarrah, PhD, and colleagues publish new study on the regulation of centriole duplication. Centriole duplication is tightly regulated throughout the cell cycle to ensure one duplication event per centriole. McLamarrah et al. show that a stepwise pattern of Ana2 phosphorylation by Plk4 facilitates proper centriole duplication providing molecular insight into the assembly process of this organelle.