• Jared Churko, PhD

    Informatics to Understand Cardiovascular Development and Disease Mechanisms

  • LEADERS

    Training Our Next Leaders in Biomedical Research

  • RESEARCH

    An Established Leader in Cutting-edge Research

  • Greg Rogers, PhD

    Investigating Mechanisms of Genomic Integrity

  • Brett Colson, PhD

    Deciphering the Structural Basis for Muscle Contraction at the Molecular Level

  • Noel Warfel, PhD

    Modeling the Effects of Hypoxia on Cancer Cells and Tumor Angiogenesis

  • Keith Maggert, PhD

    Understanding the Origins of Genome Instability

  • DISCOVERY

    A Thriving Environment for Biomedical Discovery

  • Darren Cusanovich, PhD

    Understanding How the Genome Regulates Diverse Cell Types in Development and Disease

  • Curtis Thorne, PhD

    Discovering Signals Controlling Cell Fate of Regenerative Tissues

  • Casey Romanoski, PhD

    Systems Genetics Approaches to Identify Mechanisms of Complex Diseases

  • Samantha Harris, PhD

    Understanding Myosin Binding Protein-C in Health and Disease

  • Gus Mouneimne, PhD

    Understanding How Cytoskeletal Architecture Regulates Cancer Metastasis

  • Jean Wilson, PhD

    Cell biology of barrier function in inflammatory bowel diseases

  • Tom Doetschman, PhD

    Synergistic Activities of TGFbeta Deficiency and the Gut Microbiome in Colon Cancer

Home

Message from the Chair

The mission of the Department of Cellular and Molecular Medicine (CMM) is to provide pre- and post-doctoral, medical and graduate education in an interdisciplinary environment through research activities, to advance knowledge of biological structure as related to function and disease from the molecular level to the whole organism.

Announcements

Dr. Darren Cusanovich publishes in Cell (August 2, 2018)

Darren Cusanovich, PhD, led a study published in the most recent issue of Cell presenting a single-cell atlas of chromatin (how the genome is packaged in the nucleus of a cell) patterns in adult mice based on data from almost 100,000 individual cells. Their work sheds light on how the various cell types present in mammals are able to accomplish such different functions while referencing the same genome. This resource may ultimately help us to understand precisely how human diseases develop and manifest in complex tissues.

Dr. Marco Padilla-Rodriguez publishes in Nature Communications (August 1, 2018)

Marco Padilla-Rodriguez, PhD – a recent CMM graduate from Dr. Gus Mouneimne’s lab- and colleagues have recently published a new study in Nature Communications highlighting estrogen’s dual effects of promoting tumor growth in estrogen receptor-positive (ER+) breast cancer, and suppressing tumor invasion through actin cytoskeletal remodeling.

Dr. Diana Darnell promoted to full Professor (July 2, 2018)

Congratulations to CMM's own Diana Darnell, PhD for her promotion to full Professor, Educator Scholar Track! 

Farah Bughio receives Donald G. Sheer Travel Award (June 26, 2018)

CMM would like to extend a warm congratulations to Farah Bughio (Maggert lab), recipient of a 2018 Donald G. Sheer Memorial Fund travel grant!  This fund provides stipends to graduate students to allow them to travel to scientific conferences and meetings in the health sciences to present their research.  Great job, Farah!

Dr. Curtis Thorne publishes in Developmental Cell (March 19, 2018)

Curtis Thorne, PhD, and colleagues published a new study in Developmental Cell describing a simple, scalable method to culture 2D enteroid monolayers that, surprisingly, recapitulates many of the features of in vivo intestinal tissue and can be used for high-throughput microscopy-based experiments. Using this system, they systematically perturb WNT and BMP signals to reveal a core morphogenic circuit that controls proliferation, tissue organization, and cell fate or the intestine.

Welcome to our new students! (March 16, 2018)

CMM is delighted to welcome the following new PhD students who are entering the Graduate Program in Molecular Medicine: Alice Solomon, (Romanoski Lab), Austin Conklin (Romanoski Lab) and Rhye-Samuel Kanassatega (Colson Lab).   We also extend a friendly welcome to the following Cancer Biology PhD students who will be working in labs with CMM faculty: Carly Cabel (Thorne Lab), Corbin Jensen (Warfel Lab) and Shekha Tahsin (Miranti Lab). 

Upcoming Events

Sep
25
GPMM Student Seminar - John Ryniawec, PhD Candidate
Tuesday 12:30pm
MRB 102

Oct
09
CMM Faculty Meeting
Tuesday 4:00pm
LSN 452

Oct
11
CMM Departmental Seminar - Dr. Eric Small, University of Rochester Medical Center
Thursday 4:00pm
Sarver Heart Center 4137

Nov
13
GPMM Student Seminar - Lauren Schultz, PhD Candidate
Tuesday 12:30pm
MRB 102

Spotlight

An inspiration from THE DESERT – two team-building murals by CMM Faculty and Family. ​We had a blast at Creative Juice Bar on Tuesday evening (3/6/2018)!