Cancer Cell Biology

Cancer Biology focuses on fundamental mechanisms in cancer development and progression with the long-term aim of promoting the translation of novel therapies.

Cancer Biology research covers a broad spectrum of inquiry into the mechanisms of cancer progression, including genomic and mRNA regulation, signal transduction, intracellular trafficking, cell polarity, metastasis and basic mechanisms of growth, invasion and survival. Investigators begin by utilizing a variety of tools to ask basic science questions about the initiation and progression of cancer (including model organisms and high-throughput techniques) and continue on through the pre-clinical application of these discoveries using mouse-modeling.

Primary Faculty
Associate Dean, Research-Agriculture and Life Sciences
Professor, Cellular and Molecular Medicine
(520) 621-7201

Research in our laboratory investigates mechanisms regulating lineage diversification and morphogenesis during embryogenesis.
Deputy Dean, Research Affairs
Professor, Cellular and Molecular Medicine
Professor, Radiation Oncology
Professor, Molecular and Cellular Biology
(520) 626-7553

We study the molecular mechanisms of human cancer progression and metastasis and the regulation of cell surface adhesion molecules, called integrins.
Professor, Cellular and Molecular Medicine
Professor, BIO5 Institute
(520) 626-4901

Synergistic activities of TGFbeta deficiency and the gut microbiome in colon cancer.
Associate Professor, Cellular and Molecular Medicine
Scientific Director, Cancer Biology Research Program
(520) 626-7979

Genetic analysis of genomic instability in cancer susceptibility.
Vice Dean for Innovation and Development – COM - Tucson
Department Head, Cellular and Molecular Medicine
Co-Director, Sarver Heart Center
Director, Molecular Cardiovascular Research Program
Professor, Cellular and Molecular Medicine
Professor, Molecular and Cellular Biology
Professor, BIO5 Institute
(520) 626-8113

The research in my laboratory is focused on identifying the components and molecular mechanisms regulating cytoskeletal architecture in cardiac and skeletal muscle during normal development and in disease.
Associate Professor, Cellular and Molecular Medicine Res - (Research Scholar Track)
(520) 626-8044

My research is currently focused on the role and regulation of serine protease Kallikrein 6 in metastatic colon cancer. Other research area is polyamine metabolism in inflammation-induced gastrointestinal malignancies.
Associate Professor, Cellular and Molecular Medicine
(520) 626-9545

Connection between epignetic instability and chromosome damage.
Professor, Cellular and Molecular Medicine
GIDP Chair, Cancer Biology
Director, Research / Facilities
(520) 626-4250

My overall interest is in elucidating the mechanisms that lead to disregulated cell signaling that occurs during tumorigenesis.
Professor, Cellular and Molecular Medicine
Program Leader, Prostate Cancer Research
(520) 626-2269

Defining the mechanisms by which cell adhesion and the tumor microenvironment promote prostate cancer progression and metastasis.
Assistant Professor, Cellular and Molecular Medicine
(520) 626-4616

Understanding How Cytoskeletal Architecture Regulates Cancer Metastasis
Research Assistant Professor, Cellular and Molecular Medicine
(520) 626-0391

To investigate underlying molecular profiles in cancer patient data using integrated computational analysis of multi-omics data in the context of disease outcome, treatment and progression.
Associate Professor, Cellular and Molecular Medicine
Associate Department Head, Faculty Development, Cellular and Molecular Medicine
Associate Professor, Molecular and Cellular Biology
Associate Professor, BIO5 Institute
(520) 626-3925

Understanding cellular mechanisms that regulate centrosome duplication, nuclear organization, and genomic integrity.
Professor, Cellular and Molecular Medicine
Research Scientist, Sarver Heart Center
Investigator, Center for Toxicology
(520) 626-2326

Research in this lab is focused on 3 projects. A. Regulation of epithelial-mesenchymal transition in heart development and cancer. B. Mitochondrial transfer from stem cells to myocytes. C. Congenital heart disease from exposure to trichloroethylene.
Assistant Professor/Research, Cellular and Molecular Medicine
(520) 626-9048

I am interested in research that advances our knowledge on cancers including their biology, signal transduction and novel therapeutics.
Assistant Professor, Cellular and Molecular Medicine
(520) 626-0194

Combining chemical biology and computer vision approaches to discover cellular communication mechanisms controlling cell fate, self-organization and disease progression of regenerative tissues
Assistant Professor, Cellular and Molecular Medicine
(520) 626-7756

Understanding the complex biological mechanisms that allow cancer cells to thrive in the hypoxic tumor microenvironment and developing new therapeutic strategies to oppose hypoxia-mediated therapeutic resistance.
Professor, Cellular and Molecular Medicine
Professor, BIO5 Institute
(520) 626-2557

The Wilson laboratory works on the establishment and maintenance of the integrity of the intestine through the regulation of membrane trafficking to the apical plasma membrane domain.
Affiliated Faculty
Professor, Surgery
Associate Professor, Pathology
Associate Professor, Cellular and Molecular Medicine
Professor, Ophthalmology
(520) 626-1913