Lonnie Lybarger, PhD

Associate Professor, Cellular and Molecular Medicine
Associate Professor, BIO5 Institute
Associate Professor, Immunobiology
Research Interests: 

I am passionate about educating students and supporting their professional development. I teach in the areas of histology, cell biology, and immunology to undergraduate, graduate, and medical students.

Bibliography

2020

Jamwal, D. R., D. Laubitz, C. A. Harrison, V. Figliuolo da Paz, C. M. Cox, R. Wong, M. Midura-Kiela, M. A. Gurney, D. G. Besselsen, P. Setty, et al., "Intestinal Epithelial Expression of MHCII Determines Severity of Chemical, T-Cell-Induced, and Infectious Colitis in Mice.", Gastroenterology, vol. 159, issue 4, pp. 1342-1356.e6, 2020 10. PMID: 32589883

2018

Bhagwandin, C., E. L. Ashbeck, M. Whalen, J. Bandola-Simon, P. A. Roche, A. Szajman, S. Mai Truong, B. C. Wertheim, Y. C. Klimentidis, S. Ishido, et al., "The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner.", PLoS One, vol. 13, issue 10, pp. e0204898, 2018. PMCID: PMC6200199  PMID: 30356278

2013

Phipps-Yonas, H., H. Cui, N. Sebastiao, P. S. Brunhoeber, E. Haddock, M. J. Deymier, W. Klapper, L. Lybarger, D. J. Roe, and K. Taraszka Hastings, "Low GILT Expression is Associated with Poor Patient Survival in Diffuse Large B-Cell Lymphoma.", Front Immunol, vol. 4, pp. 425, 2013. PMCID: PMC3885809  PMID: 24409177

2011

Corcoran, K., M. Jabbour, C. Bhagwandin, M. J. Deymier, D. L. Theisen, and L. Lybarger, "Ubiquitin-mediated regulation of CD86 protein expression by the ubiquitin ligase membrane-associated RING-CH-1 (MARCH1).", J Biol Chem, vol. 286, issue 43, pp. 37168-80, 2011 Oct 28. PMCID: PMC3199464  PMID: 21896490
Rizvi, S. Monem, N. Del Cid, L. Lybarger, and M. Raghavan, "Distinct functions for the glycans of tapasin and heavy chains in the assembly of MHC class I molecules.", J Immunol, vol. 186, issue 4, pp. 2309-20, 2011 Feb 15. PMCID: PMC3057457  PMID: 21263072

2010

Ordaz, M. L., N. Larmonier, and L. Lybarger, "DC-expressed MHC class I single-chain trimer-based vaccines prime cytotoxic T lymphocytes against exogenous but not endogenous antigens.", Cell Immunol, vol. 262, issue 2, pp. 141-9, 2010. PMID: 20199770

2009

Wang, B., T. M. Primeau, N. Myers, H. W. Rohrs, M. L. Gross, L. Lybarger, T. H. Hansen, and J. M. Connolly, "A single peptide-MHC complex positively selects a diverse and specific CD8 T cell repertoire.", Science, vol. 326, issue 5954, pp. 871-4, 2009 Nov 6. PMCID: PMC2828816  PMID: 19892989
Jabbour, M., E. M. Campbell, H. Fares, and L. Lybarger, "Discrete domains of MARCH1 mediate its localization, functional interactions, and posttranscriptional control of expression.", J Immunol, vol. 183, issue 10, pp. 6500-12, 2009 Nov 15. PMCID: PMC2782856  PMID: 19880452
Corcoran, K., X. Wang, and L. Lybarger, "Adapter-mediated substrate selection for endoplasmic reticulum-associated degradation.", J Biol Chem, vol. 284, issue 26, pp. 17475-87, 2009 Jun 26. PMCID: PMC2719388  PMID: 19366690

2003

Lybarger, L., X. Wang, M. R. Harris, H. W. Virgin, and T. H. Hansen, "Virus subversion of the MHC class I peptide-loading complex.", Immunity, vol. 18, issue 1, pp. 121-30, 2003 Jan. PMID: 12530981

2001

Lybarger, L., Y. Y. Yu, T. Chun, C. R. Wang, A. G. Grandea, L. Van Kaer, and T. H. Hansen, "Tapasin enhances peptide-induced expression of H2-M3 molecules, but is not required for the retention of open conformers.", J Immunol, vol. 167, issue 4, pp. 2097-105, 2001 Aug 15. PMID: 11489993