• Samantha Harris, PhD

    Understanding Myosin Binding Protein-C in Health and Disease

  • DISCOVERY

    A Thriving Environment for Biomedical Discovery

  • Tom Doetschman, PhD

    Synergistic Activities of TGFbeta Deficiency and the Gut Microbiome in Colon Cancer

  • Jared Churko, PhD

    Informatics to Understand Cardiovascular Development and Disease Mechanisms

  • Keith Maggert, PhD

    Understanding the Origins of Genome Instability

  • Casey Romanoski, PhD

    Systems Genetics Approaches to Identify Mechanisms of Complex Diseases

  • Curtis Thorne, PhD

    Discovering Signals Controlling Cell Fate of Regenerative Tissues

  • Ray Runyan, PhD

    Regulation of Cell Invasion in Development and Cancer

  • Jean Wilson, PhD

    Cell biology of barrier function in inflammatory bowel diseases

  • Julie Ledford, PhD

    Immunological Roles of Endogenous Lung Proteins

  • Darren Cusanovich, PhD

    Understanding How the Genome Regulates Diverse Cell Types in Development and Disease

  • Gus Mouneimne, PhD

    Understanding How Cytoskeletal Architecture Regulates Cancer Metastasis

  • Noel Warfel, PhD

    Modeling the Effects of Hypoxia on Cancer Cells and Tumor Angiogenesis

  • LEADERS

    Training Our Next Leaders in Biomedical Research

  • RESEARCH

    An Established Leader in Cutting-edge Research

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Message from the Chair

The mission of the Department of Cellular and Molecular Medicine (CMM) is to provide pre- and post-doctoral, medical and graduate education in an interdisciplinary environment through research activities, to advance knowledge of biological structure as related to function and disease from the molecular level to the whole organism.

Announcements

PRE-Symposium Workshop! May 15 - May 17

Pre-Symposium Workshop:  Introduction to Working with Human Pluripotent Stem Cells

The 3-day pre-symposium workshop will be held Wednesday May 15 to Friday May 17, 2019 at 12:30pm. It will provide undergraduate and graduate students, postdoctoral fellows, or research scientists a hands-on introduction to culture and manipulations of human pluripotent stem cells.

(There are a limited number of slots and selection will be determined by the symposium planning committee.)

There is no fee to attend the workshop, but registration is required.

In addition, travel costs, meals, and lodging will be covered for selected participants. Applications must be received by Friday, April 1, 2019.

https://events.research.asu.edu/statewide-symposium-regenerative-medicine

For further information contact: Jared Churko, Assistant Professor of Cellular & Molecular Medicine (520) 626-2347 or jchurko@email.arizona.edu

Event Location: 

Friday and Saturday, May 17 - 18, 2019 ASU - Sky Song, Synergy I & II, Building 3 1475 N. Scottsdale Road Scottsdale, Arizona

 

Statewide Symposium! May 17-18

Statewide Symposium in Regenerative Medicine

https://events.research.asu.edu/statewide-symposium-regenerative-medicine

The Statewide Symposium will bring together Arizona's lead scientists, clinicians, and other industry leaders in the areas of stem cell biology and regenerative medicine. Technical and scientific sessions will highlight emerging research in the areas of developmental biology, disease modeling, and translational cell therapy. A pre-conference workshop will provide select students and researchers an opportunity to receive hands-on training in pluripotent stem cell culture and manipulation. Following the meeting, a post-conference stakeholder’s forum will allow for the development of a strategic collaborative plan to foster the development of Arizona as a leader in regenerative medicine research, education, and workforce development. Due to generous support from the Arizona Board of Regents and our sponsors, there is no fee to attend the Symposium

PhD students Austin Conklin and Lauren Schultz receive ARCS Foundation Scholarships (March 4, 2019)

CMM PhD student Austin Conklin (Romanoski Lab) and PhD Candidate Lauren Schultz (Gregorio Lab) are the recipients of the prestigious 2019-20 ARCS Foundation Scholarships.  The ARCS Foundation - Phoenix Chapter - is dedicated to advancing science and technology in the US, and selects outstanding doctoral-track students in science, engineering, and medical Research with a track record of academic excellence. 

Dr. Donata Vercelli to present at UA College of Science Lecture Series (February 12, 2019)

Dr. Donata Vercelli, MD - a Professor of Cellular and Molecular Medicine - will speak as part of the renowned College of Science Lecture Series on February 12, 2019.  Her lecture, “The Microbes Shaping Our Lives” will be presented at Centennial Hall at 7pm.  A livestream of her talk will be available here, and her full lecture will be hosted and available to watch on the Lecture Series' Website. 

UA’s Genetic Counseling Graduate Program receives accreditation (February 1, 2019)

Congratulations to the University of Arizona Genetic Counseling Graduate Program (UAGCGP), which has been granted accredited by the Accreditation Council for Genetic Counseling (ACGC).  The new Master’s in Genetic Counseling program, part of the Department of Cellular and Molecular Medicine, will begin in Fall 2019.

Dr. Julie Ledford publishes in AJRCCM (December 19, 2018)

Julie Ledford, PhD - an Assistant Professor in CMM - together with colleagues in the Department of Medicine and the Asthma and Airways Disease Research Center recently published their study entitled “Club Cell Secretory Protein Deficiency Leads to Altered Lung Function” in the American Journal of Respiratory and Critical Care Medicine. While Club Cell Secretory Protein 16 (CC16) has been described as a serum biomarker for obstructive lung diseases, a distinct mechanism of action for CC16 has remained elusive.  This translational study used data from the birth cohort of the Tucson Children’s Respiratory Study (TCRS) and examined the relation of circulating CC16 levels with pulmonary function and responses to bronchial methacholine challenge from childhood up to age 32 years. In parallel, the study set out to comprehensively examine pulmonary physiology in mice sufficient or deficient in CC16.  It was discovered in both mouse and man that deficits in CC16 significantly impaired lung function and increased sensitivity to methacholine. In addition, CC16 deficient mice had increased collagen deposition, smooth muscle thickness and elevated gene expression of factors associated with lung remodeling. Findings in mice support the clinical observations that decreased CC16 levels in serum correlate with worse lung function by providing the first line of direct evidence that lack of CC16 in the lung results in dramatically altered pulmonary function and structural alterations consistent with enhanced remodeling.  PMID: 30543455

Upcoming Events

Mar
26
GPMM Student Seminar - Austin Conklin, PhD Student
Tuesday 12:30pm
MRB 102

May
15
Pre-Symposium Workshop! Introduction to Working with Human Pluripotent Stem Cells
Wednesday 12:30pm

Limited number of slots available!


May
17
Statewide Symposium May 2019
Friday 12:30pm

Statewide Symposium in Regenerative Medicine

ASU - Sky Song, Synergy I & II, Building 3 1475 N. Scottsdale Road Scottsdale, Arizona

Spotlight

Drs. Ledford and Kraft win $10K UA Shark Tank Prize

Drs. Julie Ledford, PhD (left) and Monica Kraft, MD (right) win the $10,000 prize during UA Research Day's ‘Shark Tank’ Event for their pitch on a new, inhaled therapeutic for the treatment of asthma and potentially even COPD, cystic fibrosis and pneumonia.