• The Department of Cellular and Molecular Medicine at the University of Arizona is home to leaders in many areas of biomedical research.

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  • College of Medicine iCourses provide flexible, stackable learning opportunities for pre-professional students.

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  • Amrita Vishwa Vidyapeetham University students can participate in a joint graduate degree program featuring coursework in Cellular & Molecular Medicine from UArizona—entirely in India.

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  • Dr. Donata Vercelli — Awarded $15.3M P01 grant from the NIH NIAID to study the impact of microbial exposures on the immune responses and childhood asthma across the US/Mexico border.

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Message from the Chair

The mission of the Department of Cellular and Molecular Medicine (CMM) is to provide pre- and post-doctoral, medical and graduate education in an interdisciplinary environment through research activities, to advance knowledge of biological structure as related to function and disease from the molecular level to the whole organism.

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Recent Publications

  • Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment.
    Author(s): F. Polverino; T.David Wu; J. Rojas-Quintero; X. Wang; J. Mayo; M. Tomchaney; J. Tram; S. Packard; D. Zhang; K.H. Cleveland; E. Cordoba-Lanus; C.A. Owen; A. Fawzy; G.L. Kinney; C.P. Hersh; N.N. Hansel; K. Doubleday; M. Sauler; Y. Tesfaigzi; J.G. Ledford; C. Casanova; J. Zmijewski; J. Konhilas; P.R. Langlais; R. Schnellmann; I. Rahman; M. McCormack; B. Celli
    Date Published: 2021 May 25
    PMID: 34033525
  • Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci.
    Author(s): T. Örd; K. Õunap; L. Stolze; R. Aherrahrou; V. Nurminen; I. Selvarajan; A. Toropainen; T. Lönnberg; E. Aavik; S. Ylä-Herttuala; M. Civelek; C.E. Romanoski; M.U. Kaikkonen
    Date Published: 2021 May 24
    PMID: 34024118
  • CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle.
    Author(s): M. Colpan; J. Iwanski; C.C. Gregorio
    Date Published: 2021 Mar 19
    PMCID: PMC7979805  PMID: 33742108
  • A high-throughput fluorescence lifetime-based assay to detect binding of myosin-binding protein C to F-actin.
    Author(s): T.A. Bunch; V.C. Lepak; K.M. Bortz; B.A. Colson
    Date Published: 2021 Mar 01
    PMCID: PMC7898471  PMID: 33600558
  • In the eye of the STORM: Tracking the myosin-binding protein C N terminus in heart muscle.
    Author(s): B.A. Colson
    Date Published: 2021 Mar 01
    PMCID: PMC7879487  PMID: 33566085

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Announcements

Warfel lab identifies a new role for PIM kinases in driving tumor angiogenesis. (July 6, 2021)

Work from Dr. Noel Warfel’s lab, led by recent CBIO graduate Andrea Casillas, recently published a paper in Oncogene describing a new signaling axis that promotes blood vessel growth in solid tumors.

CMM Faculty Recognized by College of Medicine – Tucson for Mentoring, Teaching, and Leadership (May 28, 2021)

CMM faculty members Dr. Carol C. Gregorio, Dr. Valerie M. Schaibley, Dr. James V. Proffitt, and Dr. Julie G. Ledford were recognized by the College of Medicine – Tucson for excellence in mentoring, teaching, and leadership.
Dr. Donata Vercelli awarded $15.3M grant from National Institute of Allergy and Infectious Disease (NIAID) (July 7, 2021)

Professor Donata Vercelli, MD, received an NIH grant to study asthma in children along the U.S.-Mexican border.
Cusanovich Lab develops new single-cell epigenomic assay and surveys gene regulation across human tissues in Science (November 12, 2020)

Work from Research Assistant Professor Darren Cusanovich, PhD's Laboratory in collaboration with his former colleagues at the University of Washington developed a new single-cell chromatin assay that can generate data on 100s of thousands or millions of cells at a time.
Dr. Darren Cusanovich receives $1.8M Maximizing Investigators’ Research Award for Early Stage Investigators (ESI MIRA) R35 from NIGMS (August 21, 2020)

Research Assistant Professor Darren Cusanovich, PhD, recently received an ESI MIRA R35 grant, a 5-year award for early career investigators from the NIGMS, for his proposal entitled "Beyond Pseudotime: Enhanced Single-cell Genomics Tools for Understanding the Temporal Dynamics of Development and Disease."

Romanoski Lab links DNA polymorphisms to individual disease risk in AJHG (June 4, 2020)

Research from Dr. Casey Romanoski's Laboratory - led by Genetics PhD student Lindsey Stolze - linked polymorphisms in people's DNA sequence with molecular characteristics of how cells convert genetic code into the building blocks for proteins.

Spotlight

Dr. Carol Gregorio was recently appointed Assistant Vice Provost for Global Health Sciences and interim Executive Director of UArizona Health Sciences Global and Online.

Drs. Curtis Thorne (left) and Koenraad Van Doorslaer (right) were featured on Tucson News KOLD-TV to discuss their high-throughput assay that tracks the effect of FDA approved drugs on novel coronavirus replication in lung cells.