Parker B. Antin, PhD

Associate Vice President for Research, Division of Agriculture, Life and Veterinary Sciences, and Cooperative Extension
Associate Dean for Research, College of Agriculture and Life Sciences
Professor, Cellular and Molecular Medicine
Professor, Molecular and Cellular Biology
Professor, BIO5 Institute

Parker Antin is Professor of Cellular and Molecular Medicine in the College of Medicine, Associate Vice President for Research for the Division of Agriculture, Life and Veterinary Medicine, and Cooperative Extension, and Associate Dean for Research in the College of Agriculture and Life Sciences. In his positions of Associate Vice President and Associate Dean, he is responsible for developing and implementing the research vision for the Colleges of Agriculture and Life Sciences, the Arizona Experiment Station and Cooperative Extension, with total combined research expenditures of approximately $70M per year. His responsibilities include oversight of research strategy and portfolio investment, grants and contracts pre award services, research intensive faculty hires and retentions, research communication and marketing, research facilities, and research compliance services. In collaboration with Division and College leadership teams, he has shared responsibilities for philanthropy, budgets and information technology.

Dr. Antin is a vertebrate developmental biologist whose research is concerned with the molecular mechanisms of embryonic development. His research has been supported by NIH, NSF, NASA, USDA, and the DOE, as well as several private foundations including the American Heart Association and the Muscular Dystrophy Association, He is the Principal Investigator of CyVerse, a $115M NSF funded cyberinfrastructure project whose mission is to design, deploy and expand a national cyberinfrastructure for life sciences research, and train scientists in its use (http://cyverse.org). With 75,000 users worldwide, CyVerse enables scientists to manage and store data and experiments, access high-performance computing, and share data and results with colleagues and the public.

Dr. Antin is also active nationally in the areas of science policy and funding for science. He is a past President of the Federation of Societies for Experimental Biology (FASEB), an umbrella science policy and advocacy organization representing 32 scientific societies and 135,000 scientists. His continued work with FASEB, along with his duties as Associate Vice President and Associate Dean for Research, and CyVerse PI, brings him frequently to Washington, DC, where he advocates for support of science and science policy positions that enhance the scientific enterprise.

Research Interests: 

I am a member of the Molecular Cardiovascular Research Program (MCRP) and the Bio5 Institute.

Molecular Medicine Grad Program: 
Yes

Bibliography

2020

Yang, J., P. Antin, G. Berx, C. Blanpain, T. Brabletz, M. Bronner, K. Campbell, A. Cano, J. Casanova, G. Christofori, et al., "Guidelines and definitions for research on epithelial-mesenchymal transition.", Nat Rev Mol Cell Biol, vol. 21, issue 6, pp. 341-352, 2020 Jun. PMID: 32300252
Malatesta, M., G. Mori, D. Acquotti, B. Campanini, A. Peracchi, P. B. Antin, and R. Percudani, "Birth of a pathway for sulfur metabolism in early amniote evolution.", Nat Ecol Evol, 2020 Jun 29. PMID: 32601391

2019

O'Hare, E. A., P. B. Antin, and M. E. Delany, "Two Proximally Close Priority Candidate Genes for diplopodia-1, an Autosomal Inherited Craniofacial-Limb Syndrome in the Chicken: MRE11 and GPR83.", J Hered, vol. 110, issue 2, pp. 194-210, 2019 03 05. PMCID: PMC6399517  PMID: 30597046

2016

Ward, A., T. O. Baldwin, and P. B. Antin, "Research data: Silver lining to irreproducibility.", Nature, vol. 532, issue 7598, pp. 177, 2016 Apr 14. PMID: 27075087
Antin, P. B., "A conversation with Rudolf Jaenisch.", Dev Dyn, vol. 245, issue 7, pp. 698-701, 2016 07. PMID: 27317898
Moly, P. K., J. R. Cooley, S. L. Zeltzer, T. A. Yatskievych, and P. B. Antin, "Gastrulation EMT Is Independent of P-Cadherin Downregulation.", PLoS One, vol. 11, issue 4, pp. e0153591, 2016. PMCID: PMC4838233  PMID: 27097030

2015

Schmid, M., J. Smith, D. W. Burt, B. L. Aken, P. B. Antin, A. L. Archibald, C. Ashwell, P. J. Blackshear, C. Boschiero, T. C Brown, et al., "Third Report on Chicken Genes and Chromosomes 2015.", Cytogenet Genome Res, vol. 145, issue 2, pp. 78-179, 2015. PMID: 26282327

2014

Antin, P. B., T. A. Yatskievych, S. Davey, and D. K. Darnell, "GEISHA: an evolving gene expression resource for the chicken embryo.", Nucleic Acids Res, vol. 42, issue Database issue, pp. D933-7, 2014 Jan. PMCID: PMC3964962  PMID: 24150938
Cooley, J. R., T. A. Yatskievych, and P. B. Antin, "Embryonic expression of the transforming growth factor beta ligand and receptor genes in chicken.", Dev Dyn, vol. 243, issue 3, pp. 497-508, 2014 Mar. PMCID: PMC3969743  PMID: 24166734
Darnell, D. K., and P. B. Antin, "LNA-based in situ hybridization detection of mRNAs in embryos.", Methods Mol Biol, vol. 1211, pp. 69-76, 2014. PMCID: PMC5148130  PMID: 25218377

2013

Lencinas, A., D. C. Chhun, K. P. Dan, K. D. Ross, E. A. Hoover, P. B. Antin, and R. B. Runyan, "Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart.", Dis Model Mech, vol. 6, issue 3, pp. 632-42, 2013 May. PMCID: PMC3634647  PMID: 23264563

2012

Chen, H., G. M. Untiveros, L. A. K. McKee, J. Perez, J. Li, P. B. Antin, and J. P. Konhilas, "Micro-RNA-195 and -451 regulate the LKB1/AMPK signaling axis by targeting MO25.", PLoS One, vol. 7, issue 7, pp. e41574, 2012. PMCID: PMC3402395  PMID: 22844503
Bobbs, A. S., A. V. Saarela, T. A. Yatskievych, and P. B. Antin, "Fibroblast growth factor (FGF) signaling during gastrulation negatively modulates the abundance of microRNAs that regulate proteins required for cell migration and embryo patterning.", J Biol Chem, vol. 287, issue 46, pp. 38505-14, 2012 Nov 09. PMCID: PMC3493895  PMID: 22995917

2011

Hardy, K. M., T. A. Yatskievych, J. Konieczka, A. S. Bobbs, and P. B. Antin, "FGF signalling through RAS/MAPK and PI3K pathways regulates cell movement and gene expression in the chicken primitive streak without affecting E-cadherin expression.", BMC Dev Biol, vol. 11, pp. 20, 2011. PMCID: PMC3071786  PMID: 21418646
Yaklichkin, S. Yu, D. K. Darnell, M. V. Pier, P. B. Antin, and S. Hannenhalli, "Accelerated evolution of 3'avian FOXE1 genes, and thyroid and feather specific expression of chicken FoxE1.", BMC Evol Biol, vol. 11, pp. 302, 2011. PMCID: PMC3207924  PMID: 21999483
Menendez, L., T. A. Yatskievych, P. B. Antin, and S. Dalton, "Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cells.", Proc Natl Acad Sci U S A, vol. 108, issue 48, pp. 19240-5, 2011 Nov 29. PMCID: PMC3228464  PMID: 22084120

2010

Antin, P. B., M. Pier, T. Sesepasara, T. A. Yatskievych, and D. K. Darnell, "Embryonic expression of the chicken Krüppel-like (KLF) transcription factor gene family.", Dev Dyn, vol. 239, issue 6, pp. 1879-87, 2010 Jun. PMCID: PMC2925473  PMID: 20503383
Lencinas, A., D. M. Broka, J. H. Konieczka, S. E. Klewer, P. B. Antin, T. D. Camenisch, and R. B. Runyan, "Arsenic exposure perturbs epithelial-mesenchymal cell transition and gene expression in a collagen gel assay.", Toxicol Sci, vol. 116, issue 1, pp. 273-85, 2010 Jul. PMCID: PMC2886855  PMID: 20308225