• The Department of Cellular and Molecular Medicine at the University of Arizona is home to leaders in many areas of biomedical research.

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Message from the Department Head

Mission: To advance basic and translational research and foster excellence in medical and graduate training, all dedicated to enhancing global wellness.

The Department of Cellular and Molecular Medicine (CMM) at the University of Arizona is committed to pushing the boundaries of biological knowledge through a comprehensive educational approach and interdisciplinary research. With a reputation for faculty-led research in complex disease pathogenesis, CMM's expertise encompasses cellular, molecular, and developmental biology, as well as anatomy and genetics. The department focuses on imaging, bioinformatics, ‘omics’, stem cells, and systems genetics, and is known for its collaborative, multidisciplinary research environment, ranking #9 in the Blue Ridge Institute for Medical Research 2023 rankings.

Recent Publications

  • Evaluation of Swab-Seq as a scalable, sensitive assay for community surveillance of SARS-CoV-2 infection.
    Author(s): H.J. Kang; S. Allison; A. Spangenberg; T. Carr; R. Sprissler; M. Halonen; D.A. Cusanovich
    Date Published: 23 FEB 2022
    PMCID: PMC8866503  PMID: 35197492
  • High mechanical conditioning by tumor extracellular matrix stiffness is a predictive biomarker for anti-fibrotic therapy in HER2-negative breast cancer.
    Author(s): M. Quintela-Fandino; B. Bermejo; E. Zamora; F. Moreno; J.Ángel Garcia-Saenz; S. Pernas; N.Martinez Jañez; D. Jiménez; E. Adrover; R. Andrés; S. Mourón; M.Jose Bueno; L. Manso; G. Viñas; E. Alba; A. Llombart-Cussac; J. Cortes; C. Tebar; D.J. Roe; A. Grant; A. Watson; R. Colomer; G. Mouneimne
    Date Published: 2024 Sep 16
    PMID: 39283720
  • Leiomodin 2 neonatal dilated cardiomyopathy mutation results in altered actin gene signatures and cardiomyocyte dysfunction.
    Author(s): J.B. Iwanski; C.T. Pappas; R.M. Mayfield; G.P. Farman; R. Ahrens-Nicklas; J.M. Churko*; C.C. Gregorio*
    Date Published: 2024 Sep 16
    PMCID: PMC11405699  PMID: 39285234
  • Investigation of lactotransferrin messenger RNA expression levels as an anti-type 2 asthma biomarker.
    Author(s): N.C. Li; N. Iannuzo; S.A. Christenson; P.R. Langlais; M. Kraft; J.G. Ledford; X. Li
    Date Published: 2024 May 24
    PMID: 38797239
  • Cooperation of immune regulators Tollip and surfactant protein A inhibits influenza A virus infection in mice.
    Author(s): N. Schaunaman; D. Cervantes; T. Nichols; M. Numata; J.G. Ledford; M. Kraft; H.Wei Chu
    Date Published: 2024 May 03
    PMCID: PMC11068576  PMID: 38702733

Recent News

Researchers discover new therapy that can reduce risk of breast cancer recurrance
Oct 24 2024 - 3:15pm

Dr. Ghassan (Gus) Mouneimne, Associate Professor of Cellular and Molecular Medicine, is working with researchers at the Spanish National Cancer Research Centers to improve diagnostic tools and treatment for breast cancer. Click to read more.


Congratulations to Dr. Julie Ledford on Successful Renewal of her R01
Sep 5 2024 - 3:45pm

Dr. Julie Ledford has been awarded $600,000 per year for the next four years - a successful renewal of her NIH/NHLBI R01 grant: "Defining mechanisms of CC16 on epithelial-driven host responses to pathogens." Congratulations to Dr. Ledford and her Co-Investigators Dr. Stefano Guerra, Dr. Joseph Vagner, and Dr. Darren Cusanovich.


CMM Welcomes Department Head Sakthivel Sadayappan, PhD, MBA
Aug 20 2024 - 1:30pm

The Department of Cellular and Molecular Medicine is thrilled to announce the appointment of Dr. Sakthivel Sadayappan, PhD, MBA, as our new department head! Click to read more.


Dr. Curtis Thorne's Cancer Research is Personal
Aug 19 2024 - 1:30pm

Curtis Thorne, PhD, brings a deeply personal perspective to his research, having battled cancer himself while his two brothers also faced their own fights with the disease. Click to read more.


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