Lonnie Lybarger, PhD

Associate Professor, Cellular and Molecular Medicine

Associate Professor, BIO5 Institute

Associate Professor, Immunobiology

Degrees

Teaching Interests

I am passionate about educating students and supporting their professional development. I teach in the areas of histology, cell biology, and immunology to undergraduate, graduate, and medical students.

Publications

Jamwal, Deepa R, et al. “Intestinal Epithelial Expression of MHCII Determines Severity of Chemical, T-Cell-Induced, and Infectious Colitis in Mice.”. Gastroenterology, vol. 159, no. 4, Oct. 2020, pp. 1342-1356.e6, https://doi.org/10.1053/j.gastro.2020.06.049.

Bhagwandin, Candida, et al. “The E3 Ubiquitin Ligase MARCH1 Regulates Glucose-Tolerance and Lipid Storage in a Sex-Specific Manner.”. PLoS One, vol. 13, no. 10, Jan. 2018, p. e0204898, https://doi.org/10.1371/journal.pone.0204898.

Phipps-Yonas, Hannah, et al. “Low GILT Expression Is Associated With Poor Patient Survival in Diffuse Large B-Cell Lymphoma.”. Front Immunol, vol. 4, 2013, p. 425, https://doi.org/10.3389/fimmu.2013.00425.

Corcoran, Kathleen, et al. “Ubiquitin-Mediated Regulation of CD86 Protein Expression by the Ubiquitin Ligase Membrane-Associated RING-CH-1 (MARCH1).”. J Biol Chem, vol. 286, no. 43, Oct. 2011, pp. 37168-80, https://doi.org/10.1074/jbc.M110.204040.

Rizvi, Syed Monem, et al. “Distinct Functions for the Glycans of Tapasin and Heavy Chains in the Assembly of MHC Class I Molecules.”. J Immunol, vol. 186, no. 4, Feb. 2011, pp. 2309-20, https://doi.org/10.4049/jimmunol.1002959.

Ordaz, Maria L, et al. “DC-Expressed MHC Class I Single-Chain Trimer-Based Vaccines Prime Cytotoxic T Lymphocytes Against Exogenous But Not Endogenous Antigens.”. Cell Immunol, vol. 262, no. 2, 2010, pp. 141-9, https://doi.org/10.1016/j.cellimm.2010.02.006.

Jabbour, Maurice, et al. “Discrete Domains of MARCH1 Mediate Its Localization, Functional Interactions, and Posttranscriptional Control of Expression.”. J Immunol, vol. 183, no. 10, Nov. 2009, pp. 6500-12, https://doi.org/10.4049/jimmunol.0901521.

Wang, Baomei, et al. “A Single Peptide-MHC Complex Positively Selects a Diverse and Specific CD8 T Cell Repertoire.”. Science, vol. 326, no. 5954, Nov. 2009, pp. 871-4, https://doi.org/10.1126/science.1177627.

Corcoran, Kathleen, et al. “Adapter-Mediated Substrate Selection for Endoplasmic Reticulum-Associated Degradation.”. J Biol Chem, vol. 284, no. 26, June 2009, pp. 17475-87, https://doi.org/10.1074/jbc.M808258200.

Lybarger, Lonnie, et al. “Virus Subversion of the MHC Class I Peptide-Loading Complex.”. Immunity, vol. 18, no. 1, Jan. 2003, pp. 121-30.

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Lonnie Lybarger, PhD

Degrees

Teaching Interests

Publications