Publications

2011

Warfel, N. A., M. Niederst, and A. C. Newton, "Disruption of the interface between the pleckstrin homology (PH) and kinase domains of Akt protein is sufficient for hydrophobic motif site phosphorylation in the absence of mTORC2.", J Biol Chem, vol. 286, issue 45, pp. 39122-9, 2011 Nov 11. PMCID: PMC3234737  PMID: 21908613
Thorne, C. A., B. LaFleur, M. Lewis, A. J. Hanson, K. K. Jernigan, D. C. Weaver, K. A. Huppert, T. W. Chen, C. Wichaidit, C. S. Cselenyi, et al., "A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts.", J Biomol Screen, vol. 16, issue 9, pp. 995-1006, 2011 Oct. PMCID: PMC3694444  PMID: 21859680
Warfel, N. A., M. Niederst, M. W. Stevens, P. M. Brennan, M. C. Frame, and A. C. Newton, "Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt.", J Biol Chem, vol. 286, issue 22, pp. 19777-88, 2011 Jun 3. PMCID: PMC3103356  PMID: 21454620
Romanoski, C. E., N. Che, F. Yin, N. Mai, D. Pouldar, M. Civelek, C. Pan, S. Lee, L. Vakili, W-P. Yang, et al., "Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1.", Circ Res, vol. 109, issue 5, pp. e27-41, 2011 Aug 19. PMCID: PMC3163234  PMID: 21737788
Ni, T. T., E. J. Rellinger, A. Mukherjee, S. Xie, L. Stephens, C. A. Thorne, K. Kim, J. Hu, E. Lee, L. Marnett, et al., "Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling.", Chem Biol, vol. 18, issue 12, pp. 1658-68, 2011 Dec 23. PMCID: PMC3645312  PMID: 22195568
Kim, J. Brian, Y-R. Xia, C. E. Romanoski, S. Lee, YH. Meng, Y-S. Shi, N. Bourquard, K. Wei Gong, Z. Port, V. Grijalva, et al., "Paraoxonase-2 modulates stress response of endothelial cells to oxidized phospholipids and a bacterial quorum-sensing molecule.", Arterioscler Thromb Vasc Biol, vol. 31, issue 11, pp. 2624-33, 2011 Nov. PMCID: PMC3244174  PMID: 21836061
Paredes, S., A. T. Branco, D. L. Hartl, K. A. Maggert, and B. Lemos, "Ribosomal DNA deletions modulate genome-wide gene expression: "rDNA-sensitive" genes and natural variation.", PLoS Genet, vol. 7, issue 4, pp. e1001376, 2011 Apr. PMCID: PMC3080856  PMID: 21533076
Whitman, S. A., C. Cover, L. Yu, D. L. Nelson, D. C. Zarnescu, and C. C. Gregorio, "Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle.", Circ Res, vol. 109, issue 3, pp. 262-71, 2011 Jul 22. PMCID: PMC3163600  PMID: 21659647
Pappas, C. T., K. T. Bliss, A. Zieseniss, and C. C. Gregorio, "The Nebulin family: an actin support group.", Trends Cell Biol, vol. 21, issue 1, pp. 29-37, 2011 Jan. PMCID: PMC3014390  PMID: 20951588
Lencinas, A., A. L. P. Tavares, J. V. Barnett, and R. B. Runyan, "Collagen gel analysis of epithelial-mesenchymal transition in the embryo heart: an in vitro model system for the analysis of tissue interaction, signal transduction, and environmental effects.", Birth Defects Res C Embryo Today, vol. 93, issue 4, pp. 298-311, 2011 Dec. PMID: 22271679
Brownlee, C. W., J. E. Klebba, D. W. Buster, and G. C. Rogers, "The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification.", J Cell Biol, vol. 195, issue 2, pp. 231-43, 2011 Oct 17. PMCID: PMC3198173  PMID: 21987638
Lamb, L. E., J. C. Zarif, and C. K. Miranti, "The androgen receptor induces integrin α6β1 to promote prostate tumor cell survival via NF-κB and Bcl-xL Independently of PI3K signaling.", Cancer Res, vol. 71, issue 7, pp. 2739-49, 2011 Apr 01. PMID: 21310825
Paz, E. A., J. Garcia-Huidobro, and N. A. Ignatenko, "Polyamines in cancer.", Adv Clin Chem, vol. 54, pp. 45-70, 2011. PMID: 21874756

2010

Thorne, C. A., A. J. Hanson, J. Schneider, E. Tahinci, D. Orton, C. S. Cselenyi, K. K. Jernigan, K. C. Meyers, B. I. Hang, A. G. Waterson, et al., "Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.", Nat Chem Biol, vol. 6, issue 11, pp. 829-36, 2010 Nov. PMCID: PMC3681608  PMID: 20890287
Alfaro, M. P., A. Vincent, S. Saraswati, C. A. Thorne, C. C. Hong, E. Lee, and P. P. Young, "sFRP2 suppression of bone morphogenic protein (BMP) and Wnt signaling mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair.", J Biol Chem, vol. 285, issue 46, pp. 35645-53, 2010 Nov 12. PMCID: PMC2975189  PMID: 20826809
Maier, R. M., M. W. Palmer, G. L. Andersen, M. J. Halonen, K. C. Josephson, R. S. Maier, F. D. Martinez, J. W. Neilson, D. A. Stern, D. Vercelli, et al., "Environmental determinants of and impact on childhood asthma by the bacterial community in household dust.", Appl Environ Microbiol, vol. 76, issue 8, pp. 2663-7, 2010 Apr. PMCID: PMC2849212  PMID: 20154107
Saraswati, S., M. P. Alfaro, C. A. Thorne, J. Atkinson, E. Lee, and P. P. Young, "Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling.", PLoS One, vol. 5, issue 11, pp. e15521, 2010 Nov 29. PMCID: PMC2993965  PMID: 21170416
Ordaz, M. L., N. Larmonier, and L. Lybarger, "DC-expressed MHC class I single-chain trimer-based vaccines prime cytotoxic T lymphocytes against exogenous but not endogenous antigens.", Cell Immunol, vol. 262, issue 2, pp. 141-9, 2010. PMID: 20199770
Romanoski, C. E., S. Lee, M. J. Kim, L. Ingram-Drake, C. L. Plaisier, R. Yordanova, C. Tilford, B. Guan, A. He, P. S. Gargalovic, et al., "Systems genetics analysis of gene-by-environment interactions in human cells.", Am J Hum Genet, vol. 86, issue 3, pp. 399-410, 2010 Mar 12. PMCID: PMC2833388  PMID: 20170901
Tonino, P., C. T. Pappas, B. D. Hudson, S. Labeit, C. C. Gregorio, and H. Granzier, "Reduced myofibrillar connectivity and increased Z-disk width in nebulin-deficient skeletal muscle.", J Cell Sci, vol. 123, issue Pt 3, pp. 384-91, 2010 Feb 01. PMCID: PMC2816184  PMID: 20053633
von Mutius, E., and D. Vercelli, "Farm living: effects on childhood asthma and allergy.", Nat Rev Immunol, vol. 10, issue 12, pp. 861-8, 2010 Dec. PMID: 21060319
Buster, D. W., J. Nye, J. E. Klebba, and G. C. Rogers, "Preparation of Drosophila S2 cells for light microscopy.", J Vis Exp, issue 40, 2010. PMCID: PMC3153891  PMID: 20543772
Rogers, G. C., "Spindle assembly: more than just microtubules.", Curr Biol, vol. 20, issue 8, pp. R364-6, 2010 Apr 27. PMID: 21749958
Tsukada, T., C. T. Pappas, N. Moroz, P. B. Antin, A. S. Kostyukova, and C. C. Gregorio, "Leiomodin-2 is an antagonist of tropomodulin-1 at the pointed end of the thin filaments in cardiac muscle.", J Cell Sci, vol. 123, issue Pt 18, pp. 3136-45, 2010 Sep 15. PMCID: PMC2931607  PMID: 20736303
Pappas, C. T., P. A. Krieg, and C. C. Gregorio, "Nebulin regulates actin filament lengths by a stabilization mechanism.", J Cell Biol, vol. 189, issue 5, pp. 859-70, 2010 May 31. PMCID: PMC2878950  PMID: 20498015

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