Publications

2012

Warfel, N. A., and A. C. Newton, "Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling.", J Biol Chem, vol. 287, issue 6, pp. 3610-6, 2012 Feb 3. PMCID: PMC3281723  PMID: 22144674
Doetschman, T., and M. Azhar, "Cardiac-specific inducible and conditional gene targeting in mice.", Circ Res, vol. 110, issue 11, pp. 1498-512, 2012 May 25. PMCID: PMC3855383  PMID: 22628574
Leinwand, L. A., J. C. Tardiff, and C. C. Gregorio, "Mutations in the sensitive giant titin result in a broken heart.", Circ Res, vol. 111, issue 2, pp. 158-61, 2012 Jul 6. PMID: 22773424
Prabhu, V. V., N. A. Warfel, and W. S. El-Deiry, "CTGF-mediated autophagy-senescence transition in tumor stroma promotes anabolic tumor growth and metastasis.", Cell Cycle, vol. 11, issue 14, pp. 2592-3, 2012 Jul 15. PMCID: PMC3409005  PMID: 22751431
Donlin, L. T., C. Andresen, S. Just, E. Rudensky, C. T. Pappas, M. Kruger, E. Y. Jacobs, A. Unger, A. Zieseniss, M-W. Dobenecker, et al., "Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization.", Genes Dev, vol. 26, issue 2, pp. 114-9, 2012 Jan 15. PMCID: PMC3273835  PMID: 22241783

2011

Lamb, L. E., J. C. Zarif, and C. K. Miranti, "The androgen receptor induces integrin α6β1 to promote prostate tumor cell survival via NF-κB and Bcl-xL Independently of PI3K signaling.", Cancer Res, vol. 71, issue 7, pp. 2739-49, 2011 Apr 01. PMID: 21310825
Thompson, E. W., R. Runyan, P. Savagner, and D. F. Newgreen, "Out of the desert: the 4th TEMTIA Meeting on new advances in development, fibrosis and cancer.", Cells Tissues Organs, vol. 193, issue 1-2, pp. 4-7, 2011. PMID: 21051880
Brownlee, C. W., J. E. Klebba, D. W. Buster, and G. C. Rogers, "The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification.", J Cell Biol, vol. 195, issue 2, pp. 231-43, 2011 Oct 17. PMCID: PMC3198173  PMID: 21987638
Paz, E. A., J. Garcia-Huidobro, and N. A. Ignatenko, "Polyamines in cancer.", Adv Clin Chem, vol. 54, pp. 45-70, 2011. PMID: 21874756
Thorne, C. A., B. LaFleur, M. Lewis, A. J. Hanson, K. K. Jernigan, D. C. Weaver, K. A. Huppert, T. W. Chen, C. Wichaidit, C. S. Cselenyi, et al., "A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts.", J Biomol Screen, vol. 16, issue 9, pp. 995-1006, 2011 Oct. PMCID: PMC3694444  PMID: 21859680
Ni, T. T., E. J. Rellinger, A. Mukherjee, S. Xie, L. Stephens, C. A. Thorne, K. Kim, J. Hu, E. Lee, L. Marnett, et al., "Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling.", Chem Biol, vol. 18, issue 12, pp. 1658-68, 2011 Dec 23. PMCID: PMC3645312  PMID: 22195568
Kim, J. Hoon, A. Cho, H. Yin, D. A. Schafer, G. Mouneimne, K. J. Simpson, K-V. Nguyen, J. S. Brugge, and D. J. Montell, "Psidin, a conserved protein that regulates protrusion dynamics and cell migration.", Genes Dev, vol. 25, issue 7, pp. 730-41, 2011 Apr 1. PMCID: PMC3070935  PMID: 21406550
Kim, J. Brian, Y-R. Xia, C. E. Romanoski, S. Lee, YH. Meng, Y-S. Shi, N. Bourquard, K. Wei Gong, Z. Port, V. Grijalva, et al., "Paraoxonase-2 modulates stress response of endothelial cells to oxidized phospholipids and a bacterial quorum-sensing molecule.", Arterioscler Thromb Vasc Biol, vol. 31, issue 11, pp. 2624-33, 2011 Nov. PMCID: PMC3244174  PMID: 21836061
Warfel, N. A., M. Niederst, and A. C. Newton, "Disruption of the interface between the pleckstrin homology (PH) and kinase domains of Akt protein is sufficient for hydrophobic motif site phosphorylation in the absence of mTORC2.", J Biol Chem, vol. 286, issue 45, pp. 39122-9, 2011 Nov 11. PMCID: PMC3234737  PMID: 21908613
Lencinas, A., A. L. P. Tavares, J. V. Barnett, and R. B. Runyan, "Collagen gel analysis of epithelial-mesenchymal transition in the embryo heart: an in vitro model system for the analysis of tissue interaction, signal transduction, and environmental effects.", Birth Defects Res C Embryo Today, vol. 93, issue 4, pp. 298-311, 2011 Dec. PMID: 22271679
Warfel, N. A., M. Niederst, M. W. Stevens, P. M. Brennan, M. C. Frame, and A. C. Newton, "Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt.", J Biol Chem, vol. 286, issue 22, pp. 19777-88, 2011 Jun 3. PMCID: PMC3103356  PMID: 21454620
Romanoski, C. E., N. Che, F. Yin, N. Mai, D. Pouldar, M. Civelek, C. Pan, S. Lee, L. Vakili, W-P. Yang, et al., "Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1.", Circ Res, vol. 109, issue 5, pp. e27-41, 2011 Aug 19. PMCID: PMC3163234  PMID: 21737788
Corcoran, K., M. Jabbour, C. Bhagwandin, M. J. Deymier, D. L. Theisen, and L. Lybarger, "Ubiquitin-mediated regulation of CD86 protein expression by the ubiquitin ligase membrane-associated RING-CH-1 (MARCH1).", J Biol Chem, vol. 286, issue 43, pp. 37168-80, 2011 Oct 28. PMCID: PMC3199464  PMID: 21896490
Paredes, S., A. T. Branco, D. L. Hartl, K. A. Maggert, and B. Lemos, "Ribosomal DNA deletions modulate genome-wide gene expression: "rDNA-sensitive" genes and natural variation.", PLoS Genet, vol. 7, issue 4, pp. e1001376, 2011 Apr. PMCID: PMC3080856  PMID: 21533076
Rizvi, S. Monem, N. Del Cid, L. Lybarger, and M. Raghavan, "Distinct functions for the glycans of tapasin and heavy chains in the assembly of MHC class I molecules.", J Immunol, vol. 186, issue 4, pp. 2309-20, 2011 Feb 15. PMCID: PMC3057457  PMID: 21263072
Whitman, S. A., C. Cover, L. Yu, D. L. Nelson, D. C. Zarnescu, and C. C. Gregorio, "Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle.", Circ Res, vol. 109, issue 3, pp. 262-71, 2011 Jul 22. PMCID: PMC3163600  PMID: 21659647
Pappas, C. T., K. T. Bliss, A. Zieseniss, and C. C. Gregorio, "The Nebulin family: an actin support group.", Trends Cell Biol, vol. 21, issue 1, pp. 29-37, 2011 Jan. PMCID: PMC3014390  PMID: 20951588

2010

Lamb, L. E., B. S. Knudsen, and C. K. Miranti, "E-cadherin-mediated survival of androgen-receptor-expressing secretory prostate epithelial cells derived from a stratified in vitro differentiation model.", J Cell Sci, vol. 123, issue Pt 2, pp. 266-76, 2010 Jan 15. PMID: 20048343
Pappas, C. T., P. A. Krieg, and C. C. Gregorio, "Nebulin regulates actin filament lengths by a stabilization mechanism.", J Cell Biol, vol. 189, issue 5, pp. 859-70, 2010 May 31. PMCID: PMC2878950  PMID: 20498015
Taylor, S. M., K. R. Nevis, H. L. Park, G. C. Rogers, S. L. Rogers, J. G. Cook, and V. L. Bautch, "Angiogenic factor signaling regulates centrosome duplication in endothelial cells of developing blood vessels.", Blood, vol. 116, issue 16, pp. 3108-17, 2010 Oct 21. PMCID: PMC2974614  PMID: 20664058

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