John Marvin Ryniawec III, PhD

Postdoctoral Research Associate

Rogers Lab

John Marvin Ryniawec III, PhD

ryniawecj@arizona.edu

Publications

Yang, Jiawen, et al. “Transient Centrosome Loss in Cultured Prostate Epithelial Cells Induces Chromosomal Instability to Produce an Oncogenic Genotype That Correlates With Poor Clinical Outcomes.”. Br J Cancer, Jan. 2026, https://doi.org/10.1038/s41416-025-03323-8.

Burns, Emma, et al. “Expanding Our View of Drosophila Centrioles.”. J Cell Sci, Dec. 2025, https://doi.org/10.1242/jcs.264338.

Ryniawec, John M, et al. “Generating CRISPR-Edited Clonal Lines of Cultured S2 Cells.”. Biol Methods Protoc, vol. 9, no. 1, 2024, p. bpae059, https://doi.org/10.1093/biomethods/bpae059.

Harryman, William L, et al. “Intermediate Risk Prostate Tumors Contain Lethal Subtypes.”. Front Urol, vol. 4, 2024, https://doi.org/10.3389/fruro.2024.1487873.

Harryman, William L, et al. “Intermediate Risk Prostate Tumors Contain Lethal Subtypes.”. Front Urol, vol. 4, 2024, https://doi.org/10.3389/fruro.2024.1487873.

Ryniawec, John M, et al. “Cep104 Is a Component of the Centriole Distal Tip Complex That Regulates Centriole Growth and Contributes to Drosophila Spermiogenesis.”. Curr Biol, vol. 33, no. 19, Oct. 2023, pp. 4202-4216.e9, https://doi.org/10.1016/j.cub.2023.08.075.

Ryniawec, John M, et al. “Polo-Like Kinase 4 Homodimerization and Condensate Formation Regulate Its Own Protein Levels But Are Not Required for Centriole Assembly.”. Mol Biol Cell, May 2023, p. mbcE22120572, https://doi.org/10.1091/mbc.E22-12-0572.

Ryniawec, John M, and Rogers, Gregory C. “Balancing the Scales: Fine-Tuning Polo-Like Kinase 4 to Ensure Proper Centriole Duplication.”. Genes Dev, vol. 36, no. 11-12, June 2022, pp. 647-9, https://doi.org/10.1101/gad.349815.122.

Ryniawec, John M, et al. “GLUT3/SLC2A3/Is/an/Endogenous/Marker/of/Hypoxia/in/Prostate/Cancer/Cell/Lines/and/Patient-Derived/Xenograft/Tumors.”. Diagnostics (Basel), vol. 12, no. 3, Mar. 2022, https://doi.org/10.3390/diagnostics12030676.

Ryniawec, John M, and Rogers, Gregory C. “Centrosome Instability: When Good Centrosomes Go Bad.”. Cell Mol Life Sci, vol. 78, no. 21-22, Nov. 2021, pp. 6775-9, https://doi.org/10.1007/s00018-021-03928-1.

McLamarrah, Tiffany A, et al. “A Molecular Mechanism for the Procentriole Recruitment of Ana2.”. J Cell Biol, vol. 219, no. 2, Feb. 2020, https://doi.org/10.1083/jcb.201905172.

Gambarotto, Davide, et al. “Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells.”. Dev Cell, vol. 50, no. 1, July 2019, pp. 11-24.e10, https://doi.org/10.1016/j.devcel.2019.04.036.

McLamarrah, Tiffany A, et al. “An Ordered Pattern of Ana2 Phosphorylation by Plk4 Is Required for Centriole Assembly.”. J Cell Biol, vol. 217, no. 4, Apr. 2018, pp. 1217-31, https://doi.org/10.1083/jcb.201605106.

Galletta, Brian J, et al. “A Centrosome Interactome Provides Insight into Organelle Assembly and Reveals a Non-Duplication Role for Plk4.”. Nat Commun, vol. 7, 2016, p. 12476, https://doi.org/10.1038/ncomms12476.