A gain-of-function mutation in the M-domain of cardiac myosin-binding protein-C increases binding to actin.

Bezold KL, Shaffer JF, Khosa JK, Hoye ER, Harris SP. "A gain-of-function mutation in the M-domain of cardiac myosin-binding protein-C increases binding to actin." J. Biol. Chem.. 2013;288(30):21496-505.