Romanoski Lab Links DNA Polymorphisms to Individual Disease Risk in AJHG (June 4, 2020)
Jun 04, 2020

Research from Dr. Casey Romanoski's Laboratory - led by Genetics PhD student Lindsey Stolze - linked polymorphisms in people's DNA sequence with molecular characteristics of how cells convert genetic code into the building blocks for proteins.

Granzier Lab Describes New Model of Nemaline Myopathy in Nature Communications
Jun 03, 2020

Johan Lindqvist, PhD and the laboratory of Henk Granzier, PhD recently published a paper in Nature Communications describing a novel mouse model of nemaline myopathy, a heterogenous disease with unclear pathological mechanisms.

Dr. Helen Amerongen Receives 2020 Faculty Mentoring Award
May 21, 2020

Helen Amerongen, PhD was recently awarded a 2020 College of Medicine Mentoring Award

Dr. Darren Cusanovich Selected for a University of Arizona Health Sciences Career Development Award
Apr 30, 2020

The University of Arizona Health Sciences Career Development Awards (CDA) program recently selected research assistant professor Darren Cusanovich, PhD as one of four recipients in its latest round of awards

Dr. Gregory Rogers Receives $2.6M Maximizing Investigators’ Research Award (MIRA) R35 from the NIGMS
Apr 29, 2020

Associate Professor Gregory Rogers, PhD, recently received an R35 MIRA grant, a 5-year award for established investigators from the NIGMS.

Dr. Thorne's Laboratory Receives COVID-19 Rapid Turn-Around Seed Grant
Apr 16, 2020

Assistant Professor Curtis Thorne, PhD in collaboration with Dr. Koenraad Van Doorslaer were awarded a Technology and Research Initiative Fund (TRIF) grant from the BIO5 Institute.

Dr. Elaheh Alizadeh Receives Community Foundation of Arizona Fellowship
Apr 01, 2020

Elaheh Alizadeh, PhD - a postdoctoral researcher in the lab of Curtis Thorne, PhD - is the 2020 recipient of the Sidney Hopkins, Mayola B. Vail, and Patricia Ann Hanson Postdoctoral Fellowship from Community Foundation for Southern Arizona.

Welcome Incoming GPMM Students (April 1, 2020)
Apr 01, 2020

The Department of Cellular and Molecular Medicine is delighted to welcome the following new Molecular Medicine PhD students to our department: Hao Zhang (Cusanovich Lab) and Yaeren Hernandez (Granzier Lab). We also extend a friendly welcome to the following PhD students who will be working in labs with CMM faculty: Selina Kindelay (Genetics GIDP - Maggert Lab) and Reeba Varghese (Cancer Bio GIDP - Thorne Lab).

Dr. Darnell Receives Two College of Medicine Outstanding Teaching Awards (February 5, 2020)
Feb 05, 2020

Professor Diana Darnell, PhD has received the 2020 College of Medicine Faculty Teaching Award.

Dr. Gregorio Elected as 2020 AACBNC Councilor (January 29, 2020)
Jan 29, 2020

Professor and Department Head Dr. Carol Gregorio was recently elected to the position of Councilor for the Association of Anatomy, Cell Biology, and Neurobiology Chairpersons.

Rogers Lab Publishes Organellogenesis Study in the Journal of Cell Biology (December 17, 2019)
Dec 17, 2019

In a new study of organelle biogenesis from the laboratory of Gregory Rogers, PhD, former CMM student and postdoc Tiffany McLamarrah and colleagues characterize an early step in centriole duplication.

CMM Master's Student Receives 2019 Centennial Achievement Award (December 3, 2019)
Dec 03, 2019

Michelle Ennabe, CMM Master's Student, is one of three Masters Awardees of this year's prestigious Centennial Achievement Award.

Mouneimne Lab Publishes Mechanosensing Study in Journal of Cell Biology (October 14, 2019)
Oct 14, 2019

In this newest study from the laboratory of Gus Mouneimne, PhD, Julieann Puleo and colleagues discovered that EVL, the Ena/VASP protein, is crucial for actin polymerization at focal adhesions (FAs). Importantly, they determined that EVL-mediated FA actin polymerization regulates FA maturation and mechanosensing, which are significant steps in mechanically-directed motility and durotactic invasion. This work is a significant contribution to our understanding of how cells interact with their microenvironment in normal and pathological contexts. PMID:31594807

Dr. Vercelli's Research Mentioned in the Washington Post (September 30, 2019)
Sep 30, 2019

Work from Donata Vercelli, PhD's laboratory recently featured in the Washington Post shows that living in traditional farming environments means living in a place that is extremely rich in microbes — the right microbes that our immune system has evolved to live with and learn from. The constellation of organisms found in soil and on farm animals programs how a child responds to allergens throughout her lifetime.

Maggert Lab Publishes Heterochromatin Study in PNAS (September 16, 2019)
Sep 16, 2019

A majority of the human genome consists elements called transposable elements – the fossils of evolutionary battles between ancient viruses and their human hosts. The human genome silences these elements by creating a specialized structure called heterochromatin on top of them. Dr.

Dr. Ledford Awarded NHLBI Grant to Study the Link Between Airway Infections and Obstructive Lung Disease (September 4, 2019)
Sep 04, 2019

Asthma and COPD are the most commonly diagnosed chronic lung diseases in the United States. While it is now recognized that a percentage of severe asthmatics develop fixed airway obstruction, little is known pertaining to the basic underlying mechanisms of this progression. Dr. Ledford's research will examine the role of club cell secreted protein (CC16) in the context of airway infection as a previously overlooked link in understanding this progression.

Drs. Cress and Rogers Awarded $2.8 Million Special Initiatives Provocative Questions Grant (August 27, 2019)
Aug 27, 2019

Anne Cress, PhD, and Gregory Rogers, PhD, received the prestigious NCI Provocative Questions Initiative grant to study molecular mechanisms of genomic alterations that contribute to early stages of prostate cancer initiation and progression. As co-PIs of this multi-PI (MPI) award, they lead an investigative team that includes Drs. Noel Warfel and Ray Nagle to investigate a link between hypoxia and organelle instability.

Thorne Lab Reconciles Scientific Standoff in Colon Cancer Research (July 30, 2019)
Jul 30, 2019

Curtis Thorne, PhD, Assistant Professor in the Department of Cellular and Molecular Medicine, and doctoral student Carly R. Cabel recently undertook an ambitious study to determine whether therapeutic targeting of LRP6 – a cell-surface receptor protein that mediates cell growth of its surrounding tissue environment - was a suitable treatment strategy for colon cancer, thus challenging the current scientific dogma and approaches to patient care. The results of Dr. Thorne and Ms. Cabel's experiments were published in a letter in the June 2019 issue of Developmental Cell.

UA Researcher and Doctoral Student Reconcile Scientific Standoff in Colon Cancer Research
Jul 30, 2019

Curtis Thorne, PhD, and UA doctoral student Carly Cabel validated findings from a 2018 collaborative study that identified a possible new therapeutic target for colon cancer – after a Harvard lab challenged the initial results.

Cress Lab Publishes in Cancer Research (July 26, 2019)
Jul 29, 2019

A major unmet clinical need is to distinguish cancer that is non-aggressive (low risk) versus those that are aggressive (high risk). Using the gene editing core service in the UA Cancer Center (led by Dr. Nathan Ellis), members of the CressLab in collaboration with two other CMM faculty (Drs. Cindy Miranti and Noel Warfel) found that tumors use a specific modification of an adhesion receptor called α6 integrin to generate invasive aggressive networks.