Publications
2021
Watson, A. W., A. D. Grant, S. S. Parker, S. Hill, M. B. Whalen, J. Chakrabarti, M. W. Harman, M. R. Roman, B. L. Forte, C. C. Gowan, et al., "Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.", Cell Rep, vol. 35, issue 13, pp. 109293, 2021 Jun 29.
PMID: 34192535
Iannuzo, N., M. Insel, C. Marshall, W. P. Pederson, K. J. Addison, F. Polverino, S. Guerra, and J. G. Ledford, "CC16 deficiency in the context of early life infection results in augmented airway responses in adult mice.", Infect Immun, pp. IAI0054821, 2021 Nov 15.
PMID: 34780280
Rivas, C. M., M. C. Yee, K. J. Addison, M. Lovett, K. Pal, J. G. Ledford, G. Dussor, T. J. Price, J. Vagner, K. A. DeFea, et al., "Novel proteinase-activated receptor-2 (PAR2) antagonist C391 inhibits Alternaria-induced human airway epithelial signaling in vitro and asthma indicators in acute exposure murine models.", Br J Pharmacol, 2021 Nov 28.
PMID: 34841515
Dy, A. Blythe C., P. R. Langlais, N. K. Barker, K. J. Addison, S. Tanyaratsrisakul, S. Boitano, S. A. Christenson, M. Kraft, D. Meyers, E. R. Bleecker, et al., "Myeloid-associated differentiation marker is a novel SP-A-associated transmembrane protein whose expression on airway epithelial cells correlates with asthma severity.", Sci Rep, vol. 11, issue 1, pp. 23392, 2021 Dec 03.
PMID: 34862427
Ellis, N., J. Zhu, M. K. Yagle, W-C. Yang, J. Huang, A. Kwako, M. M. Seidman, and M. J. Matunis, "RNF4 Regulates the BLM Helicase in Recovery From Replication Fork Collapse.", Front Genet, vol. 12, pp. 753535, 2021.
PMCID: PMC8633118 PMID: 34868226
Pederson, W. P., J. M. Cyphert-Daly, R. M. Tighe, L. G. Que, and J. G. Ledford, "Genetic variation in surfactant protein-A2 alters responses to ozone.", PLoS One, vol. 16, issue 2, pp. e0247504, 2021.
PMCID: PMC7899376 PMID: 33617569
Rico, K., S. Duan, R. L. Pandey, Y. Chen, J. T. Chakrabarti, J. Starr, Y. Zavros, T. Else, B. W. Katona, D. C. Metz, et al., "Genome analysis identifies differences in the transcriptional targets of duodenal versus pancreatic neuroendocrine tumours.", BMJ Open Gastroenterol, vol. 8, issue 1, 2021 Nov.
PMCID: PMC8576490 PMID: 34750164
Martinez, J. A., M. B. Skiba, H-H. Sherry Chow, W. M. Chew, K. Saboda, P. Lance, N. A. Ellis, and E. T. Jacobs, "A Protective Role for Arachidonic Acid Metabolites against Advanced Colorectal Adenoma in a Phase III Trial of Selenium.", Nutrients, vol. 13, issue 11, 2021 Oct 29.
PMCID: PMC8621008 PMID: 34836131
Wusterbarth, E., Y. Chen, H. Jecius, E. Krall, R. B. Runyan, R. Pandey, and V. Nfonsam, "Cartilage Oligomeric Matrix Protein, COMP may be a Better Prognostic Marker Than CEACAM5 and Correlates With Colon Cancer Molecular Subtypes, Tumor Aggressiveness and Overall Survival.", J Surg Res, vol. 270, pp. 169-177, 2021 Oct 20.
PMID: 34687957
Örd, T., K. Õunap, L. Stolze, R. Aherrahrou, V. Nurminen, I. Selvarajan, A. Toropainen, T. Lönnberg, E. Aavik, S. Ylä-Herttuala, et al., "Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci.", Circ Res, 2021 May 24.
PMID: 34024118
Pandey, R., M. Zhou, Y. Chen, D. Darmoul, C. C. Kisiel, V. N. Nfonsam, and N. A. Ignatenko, "Molecular Pathways Associated with Kallikrein 6 Overexpression in Colorectal Cancer.", Genes (Basel), vol. 12, issue 5, 2021 05 16.
PMCID: PMC8157155 PMID: 34065672
Polverino, F., T. David Wu, J. Rojas-Quintero, X. Wang, J. Mayo, M. Tomchaney, J. Tram, S. Packard, D. Zhang, K. H. Cleveland, et al., "Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment.", Am J Respir Crit Care Med, 2021 May 25.
PMID: 34033525
Watson, M. J., P. L. Berger, K. Banerjee, S. B. Frank, L. Tang, S. S. Ganguly, G. Hostetter, M. Winn, and C. K. Miranti, "Aberrant CREB1 activation in prostate cancer disrupts normal prostate luminal cell differentiation.", Oncogene, 04/2021.
PMID: 33846571
Cheng, J. N., J. B. Frye, S. A. Whitman, A. G. Kunihiro, R. Pandey, and J. L. Funk, "A Role for TGFβ Signaling in Preclinical Osteolytic Estrogen Receptor-Positive Breast Cancer Bone Metastases Progression.", Int J Mol Sci, vol. 22, issue 9, 2021 Apr 24.
PMCID: PMC8123146 PMID: 33923316
Bunch, T. A., V. C. Lepak, K. M. Bortz, and B. A. Colson, "A high-throughput fluorescence lifetime-based assay to detect binding of myosin-binding protein C to F-actin.", J Gen Physiol, vol. 153, issue 3, 2021 Mar 01.
PMCID: PMC7898471 PMID: 33600558
Colson, B. A., "In the eye of the STORM: Tracking the myosin-binding protein C N terminus in heart muscle.", J Gen Physiol, vol. 153, issue 3, 2021 Mar 01.
PMCID: PMC7879487 PMID: 33566085
Toth, R. K., and N. A. Warfel, "Targeting PIM Kinases to Overcome Therapeutic Resistance in Cancer.", Mol Cancer Ther, vol. 20, issue 1, pp. 3-10, 2021 01.
PMID: 33303645
Casillas, A. L., S. S. Chauhan, R. K. Toth, A. G. Sainz, A. N. Clements, C. C. Jensen, P. R. Langlais, C. K. Miranti, A. E. Cress, and N. A. Warfel, "Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors.", Oncogene, 2021 Jul 02.
PMID: 34211090
Conklin, A. C., H. Nishi, F. Schlamp, T. Örd, K. Õunap, M. U. Kaikkonen, E. A. Fisher, and C. E. Romanoski, "Meta-Analysis of Smooth Muscle Lineage Transcriptomes in Atherosclerosis and Their Relationships to In Vitro Models.", Immunometabolism, vol. 3, issue 3, 2021.
PMCID: PMC8232871 PMID: 34178388
Singh, N., V. R. Ramnarine, J. H. Song, R. Pandey, S. K. R. Padi, M. Nouri, V. Olive, M. Kobelev, K. Okumura, D. McCarthy, et al., "The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer.", Nat Commun, vol. 12, issue 1, pp. 7349, 2021 Dec 21.
PMID: 34934057
2020
Domcke, S., A. J. Hill, R. M. Daza, J. Cao, D. R. O'Day, H. A. Pliner, K. A. Aldinger, D. Pokholok, F. Zhang, J. H. Milbank, et al., "A human cell atlas of fetal chromatin accessibility.", Science, vol. 370, issue 6518, 2020 11 13.
PMCID: PMC7785298 PMID: 33184180
Augustus, G. J., R. M. Xicola, X. Llor, and N. A. Ellis, "Decreased copy-neutral loss of heterozygosity in African American colorectal cancers.", Genes Chromosomes Cancer, vol. 59, issue 8, pp. 454-464, 2020 08.
PMCID: PMC8045478 PMID: 32293075
Chauhan, S. S., R. K. Toth, C. C. Jensen, A. L. Casillas, D. F. Kashatus, and N. A. Warfel, "PIM kinases alter mitochondrial dynamics and chemosensitivity in lung cancer.", Oncogene, 2020 01 28.
PMID: 31992853
Younis, U. S., H. Wei Chu, M. Kraft, and J. G. Ledford, "A 20-Mer Peptide Derived from the Lectin Domain of Decreases Tumor Necrosis Factor Alpha Production during Mycoplasma pneumoniae Infection.", Infect Immun, vol. 88, issue 9, 2020 08 19.
PMCID: PMC7440763 PMID: 32513852
Hall, A., T. Fontelonga, A. Wright, K. Bugda Gwilt, J. Widrick, A. Pasut, F. Villa, C. K. Miranti, D. Gibbs, E. Jiang, et al., "Tetraspanin CD82 is necessary for muscle stem cell activation and supports dystrophic muscle function.", Skelet Muscle, vol. 10, issue 1, pp. 34, 11/2020.
PMCID: PMC7693590 PMID: 33243288