Publications
2021
Watson, A. W., A. D. Grant, S. S. Parker, S. Hill, M. B. Whalen, J. Chakrabarti, M. W. Harman, M. R. Roman, B. L. Forte, C. C. Gowan, et al., "Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.", Cell Rep, vol. 35, issue 13, pp. 109293, 2021 Jun 29.
PMID: 34192535
Iannuzo, N., M. Insel, C. Marshall, W. P. Pederson, K. J. Addison, F. Polverino, S. Guerra, and J. G. Ledford, "CC16 deficiency in the context of early life infection results in augmented airway responses in adult mice.", Infect Immun, pp. IAI0054821, 2021 Nov 15.
PMID: 34780280
Rivas, C. M., M. C. Yee, K. J. Addison, M. Lovett, K. Pal, J. G. Ledford, G. Dussor, T. J. Price, J. Vagner, K. A. DeFea, et al., "Novel proteinase-activated receptor-2 (PAR2) antagonist C391 inhibits Alternaria-induced human airway epithelial signaling in vitro and asthma indicators in acute exposure murine models.", Br J Pharmacol, 2021 Nov 28.
PMID: 34841515
Pandey, R., N. Johnson, L. Cooke, B. Johnson, Y. Chen, M. Pandey, J. Chandler, and D. Mahadevan, "Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients.", Cancers (Basel), vol. 13, issue 4, 2021 Feb 03.
PMID: 33546249
Dy, A. Blythe C., P. R. Langlais, N. K. Barker, K. J. Addison, S. Tanyaratsrisakul, S. Boitano, S. A. Christenson, M. Kraft, D. Meyers, E. R. Bleecker, et al., "Myeloid-associated differentiation marker is a novel SP-A-associated transmembrane protein whose expression on airway epithelial cells correlates with asthma severity.", Sci Rep, vol. 11, issue 1, pp. 23392, 2021 Dec 03.
PMID: 34862427
Ellis, N., J. Zhu, M. K. Yagle, W-C. Yang, J. Huang, A. Kwako, M. M. Seidman, and M. J. Matunis, "RNF4 Regulates the BLM Helicase in Recovery From Replication Fork Collapse.", Front Genet, vol. 12, pp. 753535, 2021.
PMCID: PMC8633118 PMID: 34868226
Selvarajan, I., A. Toropainen, K. M. Garske, M. López Rodríguez, A. Ko, Z. Miao, D. Kaminska, K. Õunap, T. Örd, A. Ravindran, et al., "Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease.", Am J Hum Genet, vol. 108, issue 3, pp. 411-430, 2021 03 04.
PMCID: PMC8008493 PMID: 33626337
Rico, K., S. Duan, R. L. Pandey, Y. Chen, J. T. Chakrabarti, J. Starr, Y. Zavros, T. Else, B. W. Katona, D. C. Metz, et al., "Genome analysis identifies differences in the transcriptional targets of duodenal versus pancreatic neuroendocrine tumours.", BMJ Open Gastroenterol, vol. 8, issue 1, 2021 Nov.
PMCID: PMC8576490 PMID: 34750164
Martinez, J. A., M. B. Skiba, H-H. Sherry Chow, W. M. Chew, K. Saboda, P. Lance, N. A. Ellis, and E. T. Jacobs, "A Protective Role for Arachidonic Acid Metabolites against Advanced Colorectal Adenoma in a Phase III Trial of Selenium.", Nutrients, vol. 13, issue 11, 2021 Oct 29.
PMCID: PMC8621008 PMID: 34836131
Hartiala, J. A., Y. Han, Q. Jia, J. R. Hilser, P. Huang, J. Gukasyan, W. S. Schwartzman, Z. Cai, S. Biswas, D-A. Trégouët, et al., "Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.", Eur Heart J, vol. 42, issue 9, pp. 919-933, 2021 Mar 01.
PMCID: PMC7936531 PMID: 33532862
Wusterbarth, E., Y. Chen, H. Jecius, E. Krall, R. B. Runyan, R. Pandey, and V. Nfonsam, "Cartilage Oligomeric Matrix Protein, COMP may be a Better Prognostic Marker Than CEACAM5 and Correlates With Colon Cancer Molecular Subtypes, Tumor Aggressiveness and Overall Survival.", J Surg Res, vol. 270, pp. 169-177, 2021 Oct 20.
PMID: 34687957
Örd, T., K. Õunap, L. Stolze, R. Aherrahrou, V. Nurminen, I. Selvarajan, A. Toropainen, T. Lönnberg, E. Aavik, S. Ylä-Herttuala, et al., "Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci.", Circ Res, 2021 May 24.
PMID: 34024118
Pandey, R., M. Zhou, Y. Chen, D. Darmoul, C. C. Kisiel, V. N. Nfonsam, and N. A. Ignatenko, "Molecular Pathways Associated with Kallikrein 6 Overexpression in Colorectal Cancer.", Genes (Basel), vol. 12, issue 5, 2021 05 16.
PMCID: PMC8157155 PMID: 34065672
Colpan, M., J. Iwanski, and C. C. Gregorio, "CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle.", Commun Biol, vol. 4, issue 1, pp. 365, 2021 Mar 19.
PMCID: PMC7979805 PMID: 33742108
Polverino, F., T. David Wu, J. Rojas-Quintero, X. Wang, J. Mayo, M. Tomchaney, J. Tram, S. Packard, D. Zhang, K. H. Cleveland, et al., "Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment.", Am J Respir Crit Care Med, 2021 May 25.
PMID: 34033525
Cheng, J. N., J. B. Frye, S. A. Whitman, A. G. Kunihiro, R. Pandey, and J. L. Funk, "A Role for TGFβ Signaling in Preclinical Osteolytic Estrogen Receptor-Positive Breast Cancer Bone Metastases Progression.", Int J Mol Sci, vol. 22, issue 9, 2021 Apr 24.
PMCID: PMC8123146 PMID: 33923316
Casillas, A. L., S. S. Chauhan, R. K. Toth, A. G. Sainz, A. N. Clements, C. C. Jensen, P. R. Langlais, C. K. Miranti, A. E. Cress, and N. A. Warfel, "Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors.", Oncogene, 2021 Jul 02.
PMID: 34211090
Singh, N., V. R. Ramnarine, J. H. Song, R. Pandey, S. K. R. Padi, M. Nouri, V. Olive, M. Kobelev, K. Okumura, D. McCarthy, et al., "The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer.", Nat Commun, vol. 12, issue 1, pp. 7349, 2021 Dec 21.
PMID: 34934057
Conklin, A. C., H. Nishi, F. Schlamp, T. Örd, K. Õunap, M. U. Kaikkonen, E. A. Fisher, and C. E. Romanoski, "Meta-Analysis of Smooth Muscle Lineage Transcriptomes in Atherosclerosis and Their Relationships to In Vitro Models.", Immunometabolism, vol. 3, issue 3, 2021.
PMCID: PMC8232871 PMID: 34178388
Pivniouk, V., O. Pivniouk, A. DeVries, J. L. Uhrlaub, A. Michael, D. Pivniouk, S. R. VanLinden, M. Y. Conway, S. Hahn, S. P. Malone, et al., "The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression.", J Allergy Clin Immunol, 2021 Dec 10.
PMCID: PMC8660661 PMID: 34902435
Batai, K., M. J. Trejo, Y. Chen, L. N. Kohler, P. Lance, N. A. Ellis, M. C. Cornelis, H-H. Sherry Chow, C-H. Hsu, and E. T. Jacobs, "Genome-Wide Association Study of Response to Selenium Supplementation and Circulating Selenium Concentrations in Adults of European Descent.", J Nutr, vol. 151, issue 2, pp. 293-302, 2021 02 01.
PMCID: PMC7849979 PMID: 33382417
Eedara, B. Babu, W. Alabsi, D. Encinas-Basurto, R. Polt, J. G. Ledford, and H. M. Mansour, "Inhalation Delivery for the Treatment and Prevention of COVID-19 Infection.", Pharmaceutics, vol. 13, issue 7, 2021 Jul 14.
PMCID: PMC8308954 PMID: 34371768
Chan, B. Y. H., A. Roczkowsky, W. Jung Cho, M. Poirier, C. Sergi, V. Keschrumrus, J. M. Churko, H. Granzier, and R. Schulz, "MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodelling.", Cardiovasc Res, vol. 117, issue 1, pp. 188-200, 2021 Jan 01.
PMCID: PMC7797218 PMID: 31995179
Quijada, H., T. Bermudez, C. L. Kempf, D. G. Valera, A. N. Garcia, S. M. Camp, J. H. Song, E. Franco, J. K. Burt, B. Sun, et al., "Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody.", Eur Respir J, vol. 57, issue 5, 2021 05.
PMCID: PMC8100338 PMID: 33243842
Tomchaney, M., M. Contoli, J. Mayo, S. Baraldo, S. Li, C. R. Cabel, D. A. Bull, S. Lick, J. Malo, S. Knoper, et al., "Paradoxical effects of cigarette smoke and COPD on SARS-CoV-2 infection and disease.", BMC Pulm Med, vol. 21, issue 1, pp. 275, 2021 Aug 23.
PMCID: PMC8381712 PMID: 34425811
