Publications
2021
Selvarajan, I., A. Toropainen, K. M. Garske, M. López Rodríguez, A. Ko, Z. Miao, D. Kaminska, K. Õunap, T. Örd, A. Ravindran, et al., "Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease.", Am J Hum Genet, vol. 108, issue 3, pp. 411-430, 2021 03 04.
PMCID: PMC8008493 PMID: 33626337
Hartiala, J. A., Y. Han, Q. Jia, J. R. Hilser, P. Huang, J. Gukasyan, W. S. Schwartzman, Z. Cai, S. Biswas, D-A. Trégouët, et al., "Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.", Eur Heart J, vol. 42, issue 9, pp. 919-933, 2021 Mar 01.
PMCID: PMC7936531 PMID: 33532862
Conklin, A. C., H. Nishi, F. Schlamp, T. Örd, K. Õunap, M. U. Kaikkonen, E. A. Fisher, and C. E. Romanoski, "Meta-Analysis of Smooth Muscle Lineage Transcriptomes in Atherosclerosis and Their Relationships to In Vitro Models.", Immunometabolism, vol. 3, issue 3, 2021.
PMCID: PMC8232871 PMID: 34178388
Pivniouk, V., O. Pivniouk, A. DeVries, J. L. Uhrlaub, A. Michael, D. Pivniouk, S. R. VanLinden, M. Y. Conway, S. Hahn, S. P. Malone, et al., "The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression.", J Allergy Clin Immunol, 2021 Dec 10.
PMCID: PMC8660661 PMID: 34902435
Colpan, M., J. Iwanski, and C. C. Gregorio, "CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle.", Commun Biol, vol. 4, issue 1, pp. 365, 2021 Mar 19.
PMCID: PMC7979805 PMID: 33742108
Eedara, B. Babu, W. Alabsi, D. Encinas-Basurto, R. Polt, J. G. Ledford, and H. M. Mansour, "Inhalation Delivery for the Treatment and Prevention of COVID-19 Infection.", Pharmaceutics, vol. 13, issue 7, 2021 Jul 14.
PMCID: PMC8308954 PMID: 34371768
Örd, T., K. Õunap, L. Stolze, R. Aherrahrou, V. Nurminen, I. Selvarajan, A. Toropainen, T. Lönnberg, E. Aavik, S. Ylä-Herttuala, et al., "Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci.", Circ Res, 2021 May 24.
PMID: 34024118
Chan, B. Y. H., A. Roczkowsky, W. Jung Cho, M. Poirier, C. Sergi, V. Keschrumrus, J. M. Churko, H. Granzier, and R. Schulz, "MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodelling.", Cardiovasc Res, vol. 117, issue 1, pp. 188-200, 2021 Jan 01.
PMCID: PMC7797218 PMID: 31995179
Tomchaney, M., M. Contoli, J. Mayo, S. Baraldo, S. Li, C. R. Cabel, D. A. Bull, S. Lick, J. Malo, S. Knoper, et al., "Paradoxical effects of cigarette smoke and COPD on SARS-CoV-2 infection and disease.", BMC Pulm Med, vol. 21, issue 1, pp. 275, 2021 Aug 23.
PMCID: PMC8381712 PMID: 34425811
Polverino, F., T. David Wu, J. Rojas-Quintero, X. Wang, J. Mayo, M. Tomchaney, J. Tram, S. Packard, D. Zhang, K. H. Cleveland, et al., "Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment.", Am J Respir Crit Care Med, 2021 May 25.
PMID: 34033525
Grant, A., R. M. Xicola, V. Nguyen, J. Lim, C. Thorne, B. Salhia, X. Llor, N. Ellis, and M. Padi, "Molecular drivers of tumor progression in microsatellite stable APC mutation-negative colorectal cancers.", Sci Rep, vol. 11, issue 1, pp. 23507, 2021 12 06.
PMCID: PMC8648784 PMID: 34873211
2020
Beh, S. Theng, C. Frisch, D. A. Brafman, J. Churko, J. E. Walker, G. E. Serrano, L. I. Sue, E. M. Reiman, T. G. Beach, and L-F. Lue, "Human Autopsy-Derived Scalp Fibroblast Biobanking for Age-Related Neurodegenerative Disease Research.", Cells, vol. 9, issue 11, 2020 Oct 30.
PMCID: PMC7692621 PMID: 33143239
Tolkatchev, D., G. E. Smith, L. E. Schultz, M. Colpan, G. L. Helms, J. R. Cort, C. C. Gregorio, and A. S. Kostyukova, "Leiomodin creates a leaky cap at the pointed end of actin-thin filaments.", PLoS Biol, vol. 18, issue 9, pp. e3000848, 2020 09.
PMCID: PMC7500696 PMID: 32898131
Jabart, E., J. Molho, K. Sin, B. Stansfield, S. G. Kazmouz, D. Ventro, K. Gardner, J. C. Wu, and J. M. Churko, "Single-cell protein expression of hiPSC-derived cardiomyocytes using Single-Cell Westerns.", J Mol Cell Cardiol, vol. 149, pp. 115-122, 2020 Dec.
PMCID: PMC7736541 PMID: 33010256
Rai, V., D. X. Quang, M. R. Erdos, D. A. Cusanovich, R. M. Daza, N. Narisu, L. S. Zou, J. P. Didion, Y. Guan, J. Shendure, et al., "Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures.", Mol Metab, vol. 32, pp. 109-121, 2020 02 01.
PMCID: PMC6961712 PMID: 32029221
Augustus, G. J., R. M. Xicola, X. Llor, and N. A. Ellis, "Decreased copy-neutral loss of heterozygosity in African American colorectal cancers.", Genes Chromosomes Cancer, vol. 59, issue 8, pp. 454-464, 2020 08.
PMCID: PMC8045478 PMID: 32293075
Chauhan, S. S., R. K. Toth, C. C. Jensen, A. L. Casillas, D. F. Kashatus, and N. A. Warfel, "PIM kinases alter mitochondrial dynamics and chemosensitivity in lung cancer.", Oncogene, 2020 01 28.
PMID: 31992853
Pond, K. W., K. Doubrovinski, and C. A. Thorne, "Wnt/β-catenin Signaling in Tissue Self-Organization.", Genes (Basel), vol. 11, issue 8, 2020 08 14.
PMCID: PMC7464740 PMID: 32823838
Sanman, L. E., I. W. Chen, J. M. Bieber, C. A. Thorne, L. F. Wu, and S. J. Altschuler, "Generation and Quantitative Imaging of Enteroid Monolayers.", Methods Mol Biol, vol. 2171, pp. 99-113, 2020.
PMID: 32705637
Kelly, G. T., R. Faraj, Z. Dai, A. E. Cress, and T. Wang, "A mutation found in esophageal cancer alters integrin β4 mRNA splicing.", Biochem Biophys Res Commun, vol. 529, issue 3, pp. 726-732, 2020 08 27.
PMID: 32736699
Larson, K., R. Kannaiyan, R. Pandey, Y. Chen, H. M. Babiker, and D. Mahadevan, "A Comparative Analysis of Tumors and Plasma Circulating Tumor DNA in 145 Advanced Cancer Patients Annotated by 3 Core Cellular Processes.", Cancers (Basel), vol. 12, issue 3, 2020 03 16.
PMCID: PMC7140098 PMID: 32188081
Chang, E. H., A. L. Willis, C. E. Romanoski, D. A. Cusanovich, N. Pouladi, J. Li, Y. A. Lussier, and F. D. Martinez, "RV Infections in Asthmatics Increase ACE2 Expression and Cytokine Pathways Implicated in COVID-19.", Am J Respir Crit Care Med, 2020 Jul 10.
PMID: 32649217
Sun, B. L., X. Sun, N. Casanova, A. N. Garcia, R. Oita, A. M. Algotar, S. M. Camp, V. Reyes Hernon, T. Gregory, A. E. Cress, et al., "Role of secreted extracellular nicotinamide phosphoribosyltransferase (eNAMPT) in prostate cancer progression: Novel biomarker and therapeutic target.", EBioMedicine, vol. 61, pp. 103059, 2020 Nov.
PMCID: PMC7559260 PMID: 33045468
Dy, A. B. C., and J. G. Ledford, "IL-13Rα2 Glycosylation Holds the Dance Card for Partnering with IL-13.", Am J Respir Cell Mol Biol, vol. 63, issue 3, pp. 277-278, 2020 09.
PMCID: PMC7462345 PMID: 32459972
Singh, N., S. K. R. Padi, J. J. Bearss, R. Pandey, K. Okumura, H. Beltran, J. H. Song, A. S. Kraft, and V. Olive, "PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell gene transcription and modulate tumor growth.", Mol Oncol, 2020 03 07.
PMID: 32146726